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Validation of a Seven-Gene Predictive SIGNature for the Efficacy of Immuno-Oncology PD-1 Inhibitors in Patients with Sarcoma.

2/5 보강

Clinical cancer research : an official journal of the American Association for Cancer Research 📖 저널 OA 54.5% 2022~2026 2026 Vol.32(7) p. 1258-1265 Sarcoma Diagnosis and Treatment

TL;DR This external validation confirms the seven-gene signature as a potential biomarker for predicting ICI efficacy in advanced sarcomas and plans to refine its use across sarcoma subtypes, and explore its applicability in other tumor types.

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

31 patients, with a median age of 33 years, and 45.

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

[CONCLUSIONS] This external validation confirms the seven-gene signature as a potential biomarker for predicting ICI efficacy in advanced sarcomas. Prospective studies are needed to determine the prognostic versus predictive value of SIGNIOS, refine its use across sarcoma subtypes, and explore its applicability in other tumor types.

OpenAlex 토픽 · Sarcoma Diagnosis and Treatment Cancer Immunotherapy and Biomarkers Immunotherapy and Immune Responses

Moura DS, Lopez-Marti J, Tawbi H, Keung E, Wani K, Lazar A

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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