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Evidence of Cardiotoxic Immune Activation by Triple Immune Checkpoint Blockade: A Translational Alert for Clinical Surveillance in Patients With Cancer.

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Journal of cardiovascular pharmacology 2026 Vol.87(4) p. 257-269 OA Cancer Immunotherapy and Biomarkers
TL;DR It is demonstrated that ICI triplets elicit potent immune activation against cardiomyocytes, providing the first preclinical evidence of direct cardiotoxic potential in this setting, and highlighting the need for enhanced clinical surveillance and cardio-oncology monitoring in patients receiving triple ICI combinations.
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PubMed DOI PMC OpenAlex Semantic 마지막 보강 2026-04-30
OpenAlex 토픽 · Cancer Immunotherapy and Biomarkers Chemotherapy-induced cardiotoxicity and mitigation CAR-T cell therapy research

Quagliariello V, Passariello M, Belardo M, Esposito A, Paone M, Berretta M

📖 무료 전문 🟢 PMC 전문 PMC13043227 🔓 OA PDF unpaywall · cc-by-nc-nd
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