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Trackable Tolerogenic Macrophages Integrate PD-L1 and Rapamycin Signaling to Suppress Alloimmune Responses in Transplantation.

3/5 보강

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 📖 저널 OA 91.8% 2023~2026 2026 Vol.13(21) p. e20420 cited 1 OA Immune cells in cancer

TL;DR Trackable tolerogenic macrophages are developed, engineered to overexpress PD‐L1, incorporate azide groups for bioorthogonal labeling, and encapsulate rapamycin nanoparticles (RAPA NPs) to highlight TTMs as multifunctional therapeutic cells that integrate graft homing, real‐time tracking, and dual‐pathway immunoregulation to advance precision immunotherapy in transplantation.

OpenAlex 토픽 · Immune cells in cancer CAR-T cell therapy research Phagocytosis and Immune Regulation

Wang Y, Song Y, Xie Y, Zhang J, Liu J, Wang W

📖 무료 전문 🟢 PMC 전문 PMC13073329 🔓 OA PDF unpaywall · cc-by

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