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Prevention and management of cutaneous immune-related adverse events: EADV Task Force statement.

Journal of the European Academy of Dermatology and Venereology : JEADV 2026 Vol.40(5) p. 739-759 🌐 cited 8 Cancer Immunotherapy and Biomarkers
TL;DR By identifying risk factors, recognizing early signs and implementing preventive strategies, healthcare professionals can significantly mitigate the severity of irAEs, thereby improving patient outcomes and quality of life.
OpenAlex 토픽 · Cancer Immunotherapy and Biomarkers Drug-Induced Adverse Reactions Dermatology and Skin Diseases

Fattore D, Apalla Z, Freites-Martinez A, Tommasino N, Nikolaou V, Lauletta G, Ortiz-Brugues A, Sollena P, Starace M, Gomes NMP, Koumaki D, Vigarios E, Kraehenbuehl L, Grafanaki K, Napolitano M, Sibaud V

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By identifying risk factors, recognizing early signs and implementing preventive strategies, healthcare professionals can significantly mitigate the severity of irAEs, thereby improving patient outcom

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APA Davide Fattore, Zoé Apalla, et al. (2026). Prevention and management of cutaneous immune-related adverse events: EADV Task Force statement.. Journal of the European Academy of Dermatology and Venereology : JEADV, 40(5), 739-759. https://doi.org/10.1111/jdv.70149
MLA Davide Fattore, et al.. "Prevention and management of cutaneous immune-related adverse events: EADV Task Force statement.." Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 40, no. 5, 2026, pp. 739-759.
PMID 41165224
DOI 10.1111/jdv.70149

Abstract

Cancer immunotherapy, particularly immune checkpoint inhibitors (ICI), has revolutionized oncology treatment by leveraging the immune system to recognize and eliminate cancer cells. However, despite its efficacy, immunotherapy may induce immune-related adverse events (irAEs), including dermatological events, that can range from mild rashes to severe life-threatening conditions such as toxic epidermal necrolysis. This paper aims to explore and analyse the preventive measures for cutaneous irAEs (cirAEs). By identifying risk factors, recognizing early signs and implementing preventive strategies, healthcare professionals can significantly mitigate the severity of irAEs, thereby improving patient outcomes and quality of life.

MeSH Terms

Humans; Immune Checkpoint Inhibitors; Immunotherapy; Drug Eruptions; Skin Diseases; Risk Factors; Stevens-Johnson Syndrome; Advisory Committees

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