Laryngeal metastasis from a thumb melanoma after a 5-year disease-free interval: A case of acute airway presentation and review of the literature.
TL;DR
The case of a 55-year-old woman with a history of thumb melanoma treated 5 years prior, who presented with laryngeal dyspnea, highlights the diagnostic challenges, the potential for aggressive curative treatment in oligometastatic disease, and the need for lifelong surveillance in melanoma patients.
OpenAlex 토픽 ·
Cutaneous Melanoma Detection and Management
Cancer Diagnosis and Treatment
Head and Neck Cancer Studies
The case of a 55-year-old woman with a history of thumb melanoma treated 5 years prior, who presented with laryngeal dyspnea, highlights the diagnostic challenges, the potential for aggressive curativ
APA
Achraf Amine Sbai, Issam Berrajaa, et al. (2026). Laryngeal metastasis from a thumb melanoma after a 5-year disease-free interval: A case of acute airway presentation and review of the literature.. Radiology case reports, 21(5), 2228-2234. https://doi.org/10.1016/j.radcr.2026.01.093
MLA
Achraf Amine Sbai, et al.. "Laryngeal metastasis from a thumb melanoma after a 5-year disease-free interval: A case of acute airway presentation and review of the literature.." Radiology case reports, vol. 21, no. 5, 2026, pp. 2228-2234.
PMID
41852460
Abstract
Metastatic malignant melanoma to the larynx is an exceptionally rare clinical entity. We report the case of a 55-year-old woman with a history of thumb melanoma treated 5 years prior, who presented with laryngeal dyspnea. Imaging revealed a large, non-enhancing laryngeal mass infiltrating all 3 levels, with thyroid cartilage lysis and an ipsilateral metastatic cervical lymph node. Following emergency tracheotomy, histopathology confirmed metastatic melanoma (HMB-45+, Melan-A+). The patient underwent total laryngectomy with bilateral neck dissection, followed by adjuvant nivolumab immunotherapy. At the 1-year follow-up, she shows no evidence of recurrence with good stoma function and manageable immunotherapy-related fatigue. This case highlights the diagnostic challenges, the potential for aggressive curative treatment in oligometastatic disease, and underscores the need for lifelong surveillance in melanoma patients.