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Spatial and Bulk Transcriptomics Reveal Distinct Molecular Signatures in Kaposi Sarcoma with and Without other KSHV-Associated Diseases.

1/5 보강

medRxiv : the preprint server for health sciences 📖 저널 OA 100% 2023~2026 2025

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

환자: KS and concurrent KAD (KS+KAD) using GeoMx digital spatial profiling (DSP) platform

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

[CONCLUSIONS] Bulk and spatial transcriptomic profiling of archival HIV-associated KS lesions revealed disease-specific molecular programs associated with concurrent KAD that altered tumor and microenvironment features. These findings demonstrate the heterogeneity of KS lesions that may guide future studies on KS pathogenesis and potential therapeutic targets.

Chadwick Q, Cauley N, Mercado-Matos J, Afsari B, Wu X, Bassel L

📖 무료 전문 🟢 PMC 전문 PMC12706615

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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