Acute vision loss associated with vincristine therapy in T cell lymphoma.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
환자: T cell lymphoblastic lymphoma who developed sudden bilateral visual impairment following the third cycle of vincristine-based chemotherapy
I · Intervention 중재 / 시술
high-dose intravenous methylprednisolone along with pyridoxine supplementation, resulting in marked visual recovery within days
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
This case highlights a potentially reversible but under-recognised complication of vincristine therapy. Early recognition and timely intervention are crucial to prevent permanent visual disability.
Vincristine, a widely used chemotherapeutic agent, may rarely cause optic neuropathy leading to acute vision loss.
APA
Paruthi A, Srivastava S, et al. (2025). Acute vision loss associated with vincristine therapy in T cell lymphoma.. BMJ case reports, 18(12). https://doi.org/10.1136/bcr-2025-269563
MLA
Paruthi A, et al.. "Acute vision loss associated with vincristine therapy in T cell lymphoma.." BMJ case reports, vol. 18, no. 12, 2025.
PMID
41475853 ↗
Abstract 한글 요약
Vincristine, a widely used chemotherapeutic agent, may rarely cause optic neuropathy leading to acute vision loss. We describe a patient with T cell lymphoblastic lymphoma who developed sudden bilateral visual impairment following the third cycle of vincristine-based chemotherapy. Extensive evaluation excluded alternative causes, including central nervous system infiltration, opportunistic infections and metabolic disturbances. A diagnosis of vincristine-induced optic neuropathy was made. The patient received high-dose intravenous methylprednisolone along with pyridoxine supplementation, resulting in marked visual recovery within days. This case highlights a potentially reversible but under-recognised complication of vincristine therapy. Early recognition and timely intervention are crucial to prevent permanent visual disability.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- A Phase I Study of Hydroxychloroquine and Suba-Itraconazole in Men with Biochemical Relapse of Prostate Cancer (HITMAN-PC): Dose Escalation Results.
- Self-management of male urinary symptoms: qualitative findings from a primary care trial.
- Clinical and Liquid Biomarkers of 20-Year Prostate Cancer Risk in Men Aged 45 to 70 Years.
- Diagnostic accuracy of Ga-PSMA PET/CT versus multiparametric MRI for preoperative pelvic invasion in the patients with prostate cancer.
- Clinical Presentation and Outcomes of Patients Undergoing Surgery for Thyroid Cancer.
- Association of patient health education with the postoperative health related quality of life in low- intermediate recurrence risk differentiated thyroid cancer patients.