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Platelet Recovery and Its Impact on Outcomes After Allogeneic Hematopoietic Stem Cell Transplantation: A Japanese Nationwide Retrospective Study.

American journal of hematology 2026 Vol.101(1) p. 193-197

Kurita N, Maruo K, Kimura F, Kuwatsuka Y, Matsukawa T, Konuma T, Kobayashi S, Sakata-Yanagimoto M, Doki N, Tanaka M, Uchida N, Nishida T, Sawa M, Hasegawa Y, Nakamae H, Ota S, Onizuka M, Fukuda T, Hiramoto N, Kawakita T, Asada N, Ishimaru F, Kanda J, Tabuchi K, Atsuta Y, Nakasone H

📝 환자 설명용 한 줄

In this Japanese registry-based analysis of 9105 adult patients with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation, a marked difference in survival was observed based on

🔬 핵심 임상 통계 (초록에서 자동 추출 — 원문 검증 권장)
  • p-value p < 0.001

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BibTeX ↓ RIS ↓
APA Kurita N, Maruo K, et al. (2026). Platelet Recovery and Its Impact on Outcomes After Allogeneic Hematopoietic Stem Cell Transplantation: A Japanese Nationwide Retrospective Study.. American journal of hematology, 101(1), 193-197. https://doi.org/10.1002/ajh.70124
MLA Kurita N, et al.. "Platelet Recovery and Its Impact on Outcomes After Allogeneic Hematopoietic Stem Cell Transplantation: A Japanese Nationwide Retrospective Study.." American journal of hematology, vol. 101, no. 1, 2026, pp. 193-197.
PMID 41159671
DOI 10.1002/ajh.70124

Abstract

In this Japanese registry-based analysis of 9105 adult patients with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation, a marked difference in survival was observed based on platelet levels: ≤ 20 × 10/L, 20-50 × 10/L, and > 50 × 10/L. The number of patients with thrombocytopenia receiving cord blood (CB, 39%) was significantly larger than those receiving unrelated bone marrow (uBM, 17%) on Day 50 (p < 0.001); however, this difference disappeared on Day 100 posttransplantation (both 11%, p = 0.4).

MeSH Terms

Humans; Hematopoietic Stem Cell Transplantation; Retrospective Studies; Adult; Male; Middle Aged; Japan; Female; Transplantation, Homologous; Aged; Platelet Count; Thrombocytopenia; Registries; Adolescent; Blood Platelets; Cord Blood Stem Cell Transplantation; Young Adult; Treatment Outcome; Allografts; Leukemia; Leukemia, Myeloid, Acute; East Asian People