Rosai-Dorfman disease mimicking testicular malignancy in a patient with marginal zone lymphoma of the lung.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
15 cases described to date, and its association with haematological malignancy remains poorly understood.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Testicular RDD is extremely uncommon, with only ~15 cases described to date, and its association with haematological malignancy remains poorly understood. Recognition of this entity is essential to avoid unnecessary oncological treatment.
Rosai-Dorfman-Destombes disease (RDD) is a rare, benign histiocytic disorder, most often involving lymph nodes but showing extranodal manifestations in nearly 50% of cases, particularly in the skin an
APA
Lee-Diaz E, Vaughan VC, et al. (2026). Rosai-Dorfman disease mimicking testicular malignancy in a patient with marginal zone lymphoma of the lung.. BMJ case reports, 19(1). https://doi.org/10.1136/bcr-2025-265657
MLA
Lee-Diaz E, et al.. "Rosai-Dorfman disease mimicking testicular malignancy in a patient with marginal zone lymphoma of the lung.." BMJ case reports, vol. 19, no. 1, 2026.
PMID
41500717 ↗
Abstract 한글 요약
Rosai-Dorfman-Destombes disease (RDD) is a rare, benign histiocytic disorder, most often involving lymph nodes but showing extranodal manifestations in nearly 50% of cases, particularly in the skin and upper respiratory tract. A hallmark histological feature is emperipolesis-large CD68+ and S100+ histiocytes containing intact inflammatory cells. We report a unique case of bilateral testicular RDD in a man with prior extranodal marginal zone lymphoma of the lungs. Three years after lymphoma remission, he presented with bilateral testicular enlargement. Ultrasound and positron emission tomography/CT showed diffuse hypoechoic parenchyma with metabolic activity suggestive of malignancy. Bilateral orchiectomy revealed tan-yellow, fleshy masses infiltrating the testicular parenchyma. Histology confirmed RDD with emperipolesis and S100+/CD68+/CD1a- phenotype. Testicular RDD is extremely uncommon, with only ~15 cases described to date, and its association with haematological malignancy remains poorly understood. Recognition of this entity is essential to avoid unnecessary oncological treatment.
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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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