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Clinical practice guidelines for the diagnosis and management of chronic lymphocytic leukemia in Saudi Arabia: consensus statement by an expert panel.

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Frontiers in medicine 📖 저널 OA 100% 2021: 5/5 OA 2022: 14/14 OA 2023: 10/10 OA 2024: 14/14 OA 2025: 175/175 OA 2026: 119/119 OA 2021~2026 2025 Vol.12() p. 1719364
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유사 논문
P · Population 대상 환자/모집단
환자: CLL have improved substantially over time, largely due to the emergence of new, effective, and safer therapeutic options across different stages of the disease
I · Intervention 중재 / 시술
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C · Comparison 대조 / 비교
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O · Outcome 결과 / 결론
This paper represents a focused review and consensus guideline from an expert panel in Saudi Arabia to guide diagnosis and management of CLL nationally. Recommendations are provided based on the available literature evidence and following consensus discussion among the expert panel, covering the diagnosis, staging, and management of CLL in the first line and relapsed/refractory settings.

Alotaibi G, Aleem A, Absi A, Alaskar AS, Alfraih F, Alhejazi A

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Chronic lymphocytic leukemia (CLL) is the most common adult leukemia and represents a significant proportion of leukemias diagnosed in the Western countries but the true incidence and relative frequen

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↓ .bib ↓ .ris
APA Alotaibi G, Aleem A, et al. (2025). Clinical practice guidelines for the diagnosis and management of chronic lymphocytic leukemia in Saudi Arabia: consensus statement by an expert panel.. Frontiers in medicine, 12, 1719364. https://doi.org/10.3389/fmed.2025.1719364
MLA Alotaibi G, et al.. "Clinical practice guidelines for the diagnosis and management of chronic lymphocytic leukemia in Saudi Arabia: consensus statement by an expert panel.." Frontiers in medicine, vol. 12, 2025, pp. 1719364.
PMID 41613320 ↗

Abstract

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia and represents a significant proportion of leukemias diagnosed in the Western countries but the true incidence and relative frequency of CLL compared with other leukemias in Saudi Arabia are not well defined. Survival outcomes in patients with CLL have improved substantially over time, largely due to the emergence of new, effective, and safer therapeutic options across different stages of the disease. There is a need for clear guidance in the optimal selection of patients for therapy, as well as guidance on therapeutic decision-making to achieve the best outcomes and reduce adverse events seen with the treatment. One of the important purposes of development of local guidelines is to unify the management approach of CLL and to facilitate and optimize early patient referral. This paper represents a focused review and consensus guideline from an expert panel in Saudi Arabia to guide diagnosis and management of CLL nationally. Recommendations are provided based on the available literature evidence and following consensus discussion among the expert panel, covering the diagnosis, staging, and management of CLL in the first line and relapsed/refractory settings.

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