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Long-term survival and successful pregnancy in a Nigerian woman with concurrent diagnosis of non-Hodgkin lymphoma and chronic myeloid leukemia: a case report.

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Journal of medical case reports 📖 저널 OA 99.1% 2021: 3/3 OA 2022: 4/4 OA 2023: 8/8 OA 2024: 11/11 OA 2025: 29/29 OA 2026: 41/42 OA 2021~2026 2026 Vol.20(1) p. 41 OA
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Ahmed IO, Ogunrinde VO, Asafa MA, Agim MB, Adeleke AA, Ayodele SO

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[BACKGROUND] Managing synchronous cancers can be complex, often requiring multiple agents, which increases the risk of adverse drug reactions that could negatively impact patient survival.

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APA Ahmed IO, Ogunrinde VO, et al. (2026). Long-term survival and successful pregnancy in a Nigerian woman with concurrent diagnosis of non-Hodgkin lymphoma and chronic myeloid leukemia: a case report.. Journal of medical case reports, 20(1), 41. https://doi.org/10.1186/s13256-025-05773-3
MLA Ahmed IO, et al.. "Long-term survival and successful pregnancy in a Nigerian woman with concurrent diagnosis of non-Hodgkin lymphoma and chronic myeloid leukemia: a case report.." Journal of medical case reports, vol. 20, no. 1, 2026, pp. 41.
PMID 41572382 ↗

Abstract

[BACKGROUND] Managing synchronous cancers can be complex, often requiring multiple agents, which increases the risk of adverse drug reactions that could negatively impact patient survival. The risk of chemotherapy-induced infertility may also be higher, making pregnancy nearly impossible. The aim is to report long-term survival and successful pregnancy in a 30-year-old Nigerian woman with synchronous BCR::ABL1 positive chronic myeloid leukemia and B-cell non-Hodgkin lymphoma.

[CASE PRESENTATION] The patient is a 30-year-old Nigerian woman referred by a general practitioner with a diagnosis of synchronous BCR::ABL1 positive chronic phase chronic myeloid leukemia and B-cell non-Hodgkin lymphoma. The patient was managed concurrently with a combination of R-CHOP and imatinib mesylate and achieved remission; 5 years into therapy, the patient was lost to follow-up, only to present to the clinic 2 years later with a 1-month-old baby boy. Re-evaluation showed a loss of hematological and molecular remission in chronic myeloid leukemia but not in non-Hodgkin lymphoma. Breastfeeding was stopped and then resumed on imatinib. She subsequently went into remission and is currently doing well on imatinib.

[CONCLUSION] Although managing multiple cancers in an individual may be challenging, we reported long-term survival and successful pregnancy in a 30-year-old Nigerian woman with concurrent chronic myeloid leukemia and non-Hodgkin lymphoma.

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