A Rare Case of Fluid Overload-Associated Large B-Cell Lymphoma in a Patient With Hepatitis C Cirrhosis.
A 54-year-old man with hepatitis C cirrhosis presented with apparent spontaneous bacterial peritonitis, but further work-up confirmed the diagnosis of fluid overload-associated large B-cell lymphoma (
APA
Shelukar S, Agarwal A, et al. (2026). A Rare Case of Fluid Overload-Associated Large B-Cell Lymphoma in a Patient With Hepatitis C Cirrhosis.. ACG case reports journal, 13(1), e01970. https://doi.org/10.14309/crj.0000000000001970
MLA
Shelukar S, et al.. "A Rare Case of Fluid Overload-Associated Large B-Cell Lymphoma in a Patient With Hepatitis C Cirrhosis.." ACG case reports journal, vol. 13, no. 1, 2026, pp. e01970.
PMID
41602510
Abstract
A 54-year-old man with hepatitis C cirrhosis presented with apparent spontaneous bacterial peritonitis, but further work-up confirmed the diagnosis of fluid overload-associated large B-cell lymphoma (FOA-LBCL). FOA-LBCL is a recently recognized entity with limited data on pathogenesis and treatment. Flow cytometry and cytological evaluation of ascitic fluid were key in establishing the diagnosis, whereas peripheral blood flow cytometry and imaging studies helped to exclude alternate infectious causes and secondary involvement by other lymphomas. We report a unique case of FOA-LBCL requiring multidisciplinary diagnosis and management.