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Clonal Complexity Defines Distinct Tumor-Intrinsic Biology and Prognosis in Diffuse Large B-Cell Lymphoma.

1/5 보강

Cancer medicine 📖 저널 OA 96.3% 2022~2026 2026 Vol.15(2) p. e71597 OA

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

환자: advanced-stage DLBCL (n = 74) by calculating the clonal composition (CC) number

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

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O · Outcome 결과 / 결론

Furthermore, Poly-ABC tumors carried a significantly higher number of pathogenic mutations as compared with Mono-ABC tumors (p = 0.0147). [CONCLUSION] These results suggest that clonal complexity captures tumor-intrinsic features and biological diversity in DLBCL, especially in the ABC subtype, offering novel insights into the disease pathogenesis.

Haeno T, Sakai K, Minamoto S, Nakatsu D, De Velasco MA, Rai S

📖 무료 전문 🟢 PMC 전문 PMC12863995 🔓 OA PDF unpaywall · cc-by

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