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Soluble FcεRI is increased in advanced mastocytosis and acts as a negative regulator of mast cell expansion and activation.

1/5 보강

The Journal of allergy and clinical immunology 2026 OA

PICO 자동 추출 (휴리스틱, conf 2/4)

P · Population 대상 환자/모집단

114 patients with mastocytosis, including cutaneous mastocytosis (n = 12), indolent SM (n = 67), smoldering SM (n = 5), SM with associated hematologic neoplasm (n = 17), aggressive SM (n = 9), and MC leukemia (n = 4).

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

we found that a clearly elevated sFcεRI level in SM correlates with poor survival and a lower risk of vascular instability.

Stefanzl G, Kopanja S, Ivanov D, Greiner G, Hoermann G, Arock M

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