Survival in mantle cell lymphoma patients burdened by a second primary malignancy.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: SPMs versus matched non-lymphoma individuals with comparable malignancies and MCL patients without SPMs, respectively
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
In Swedish MCL patients with SPMs, deaths were attributed to subsequent hematologic malignancies (9%), solid cancers (14%), primary MCL (23%), non-cancer causes (11%), with 40% still alive. Development of SPMs in MCL is associated with substantially higher mortality, supporting long-term surveillance and proactive management of late complications.
Second primary malignancies (SPMs) increasingly affect mantle cell lymphoma (MCL) survivors.
- 95% CI 1.4-1.9
APA
Abalo KD, Trab T, et al. (2026). Survival in mantle cell lymphoma patients burdened by a second primary malignancy.. Leukemia & lymphoma, 67(4), 821-831. https://doi.org/10.1080/10428194.2025.2606211
MLA
Abalo KD, et al.. "Survival in mantle cell lymphoma patients burdened by a second primary malignancy.." Leukemia & lymphoma, vol. 67, no. 4, 2026, pp. 821-831.
PMID
41511911 ↗
Abstract 한글 요약
Second primary malignancies (SPMs) increasingly affect mantle cell lymphoma (MCL) survivors. In nationwide Danish and Swedish cohorts (2000-2020), we evaluated overall survival among MCL patients with SPMs versus matched non-lymphoma individuals with comparable malignancies and MCL patients without SPMs, respectively. Of 3094 MCL survivors, 19% in Denmark and 15% in Sweden developed an SPM, with a median of three years from MCL diagnosis to first SPM. MCL patients with SPMs had about double the mortality risk compared with non-lymphoma counterparts (pooled HR 2.1, 95% confidence interval (CI) 1.3-3.5), and worse survival than MCL patients without SPMs (pooled HR 1.6, 95% CI 1.4-1.9). In Swedish MCL patients with SPMs, deaths were attributed to subsequent hematologic malignancies (9%), solid cancers (14%), primary MCL (23%), non-cancer causes (11%), with 40% still alive. Development of SPMs in MCL is associated with substantially higher mortality, supporting long-term surveillance and proactive management of late complications.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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