Probable disseminated cryptococcosis relapse in a patient with Hodgkin's lymphoma treated with induction therapy resumption and autologous stem cell transplant.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
환자: Hodgkin's lymphoma who experienced a probable relapse in disseminated cryptococcosis during the consolidation phase of treatment
I · Intervention 중재 / 시술
autologous stem cell transplantation (ASCT), which resulted in sustained lymphoma remission
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
The patient demonstrated sustained clinical and radiological improvement at seven months post-ASCT, notwithstanding the presence of active cryptococcosis. This suggests that ASCT appears to be safe and feasible when the prognosis of the underlying hematological malignancy warrants its use.
Cryptococcus species are fungi that primarily cause infections in immunocompromised patients.
APA
Bes-Berlandier H, Stellmann JP, et al. (2026). Probable disseminated cryptococcosis relapse in a patient with Hodgkin's lymphoma treated with induction therapy resumption and autologous stem cell transplant.. Journal de mycologie medicale, 36(1), 101603. https://doi.org/10.1016/j.mycmed.2026.101603
MLA
Bes-Berlandier H, et al.. "Probable disseminated cryptococcosis relapse in a patient with Hodgkin's lymphoma treated with induction therapy resumption and autologous stem cell transplant.." Journal de mycologie medicale, vol. 36, no. 1, 2026, pp. 101603.
PMID
41544476 ↗
Abstract 한글 요약
Cryptococcus species are fungi that primarily cause infections in immunocompromised patients. In cases of hematologic malignancies, it can result in central nervous system and disseminated infections which are associated with high morbidity and case-fatality rate. We present the case of a patient with Hodgkin's lymphoma who experienced a probable relapse in disseminated cryptococcosis during the consolidation phase of treatment. After prolonged induction therapy with amphotericin B and flucytosine, followed by isavuconazole maintenance, the patient achieved a favourable outcome. Six months after relapse of cryptococcosis, the patient underwent autologous stem cell transplantation (ASCT), which resulted in sustained lymphoma remission. The cryptococcosis was successfully contained. This case highlights the need for clinicians to consider reintroducing IT in patients who experience clinical and radiological worsening during the consolidation phase. The patient demonstrated sustained clinical and radiological improvement at seven months post-ASCT, notwithstanding the presence of active cryptococcosis. This suggests that ASCT appears to be safe and feasible when the prognosis of the underlying hematological malignancy warrants its use.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
- Humans
- Cryptococcosis
- Hodgkin Disease
- Transplantation
- Autologous
- Recurrence
- Antifungal Agents
- Amphotericin B
- Induction Chemotherapy
- Male
- Nitriles
- Antineoplastic Combined Chemotherapy Protocols
- Flucytosine
- Middle Aged
- Hematopoietic Stem Cell Transplantation
- Pyridines
- Adult
- Immunocompromised Host
- Female
- Stem Cell Transplantation
- Triazoles
- Autologous stem cell transplant
- Hodgkin's lymphoma
- Relapse
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