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Frequent NPM1 mutation, monoblastic/monocytic origin and prognostic significance of organ and system involvement in myeloid sarcoma: a multicenter study.

1/5 보강
The journal of pathology. Clinical research 2026 Vol.12(2) p. e70079 OA
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 3/4)

유사 논문
P · Population 대상 환자/모집단
154 patients with MS or LC, 169 samples were analyzed by morphology, immunohistochemistry, and fluorescent in situ hybridization, and a subset by additional sequencing [TP53].
I · Intervention 중재 / 시술
allogeneic hematopoietic stem cell transplantation showed significantly improved survival
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
In conclusion, this multicenter study suggests that most MS are of myelomonocytic/monoblastic origin, a high proportion of them are NPM1 mutated, and may lack expression of MPO and CD34.

Jenei A, Kajtár B, László T, Juratli HA, Vida L, Szepesi Á


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