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Anti-CD7 fratricide-resistant chimeric antigen receptor T cells for relapsed/refractory acute myeloid leukemia.

1/5 보강
Blood 📖 저널 OA 33.2% 2026
Retraction 확인
출처
PubMed DOI

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
환자: relapsed/refractory CD7+ acute myeloid leukemia resulting in measurable residual disease negativity
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Autologous second-generation CD7-directed CAR T-cells, expressing an anti-CD7 protein expression blocker to prevent self-killing fratricide, were infused in three pediatric/young adult patients with relapsed/refractory CD7+ acute myeloid leukemia resulting in measurable residual disease negativity. The safety profile was favorable.

Becilli M, Merli P, Algeri M, Del Bufalo F, Pagliara D, Bertaina V, Agrati C, Rosignoli C, Cefalo MG, Boccieri E, Di Cecca S, Iaffaldano L, Lee Y, De Angelis B, Meshinchi S, Quintarelli C, Campana D, Locatelli F

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓
📝 환자 설명용 한 줄

Autologous second-generation CD7-directed CAR T-cells, expressing an anti-CD7 protein expression blocker to prevent self-killing fratricide, were infused in three pediatric/young adult patients with r

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↓ .bib ↓ .ris
APA Becilli M, Merli P, et al. (2026). Anti-CD7 fratricide-resistant chimeric antigen receptor T cells for relapsed/refractory acute myeloid leukemia.. Blood. https://doi.org/10.1182/blood.2025032299
MLA Becilli M, et al.. "Anti-CD7 fratricide-resistant chimeric antigen receptor T cells for relapsed/refractory acute myeloid leukemia.." Blood, 2026.
PMID 41774512
DOI 10.1182/blood.2025032299

Abstract

Autologous second-generation CD7-directed CAR T-cells, expressing an anti-CD7 protein expression blocker to prevent self-killing fratricide, were infused in three pediatric/young adult patients with relapsed/refractory CD7+ acute myeloid leukemia resulting in measurable residual disease negativity. The safety profile was favorable.