The potential use of cyclosporine in reconstructive surgery.
【연구 목적】 사이클로스포린(cyclosporine)이 장기 이식에서 입증된 선택적 면역억제제의 가치를 바탕으로, 재건 수술 분야에서 장기적인 생존을 위한 단기 치료의 가능성과 골, 근육, 신경, 정맥 동종 이식(allograft)의 사용에 대한 기존 관행을 변화시킬 잠재력을 규명하고자 하였다.
APA
Towpik E, Kupiec-Weglinski JW, Tilney NL (1985). The potential use of cyclosporine in reconstructive surgery.. Plastic and reconstructive surgery, 76(2), 312-22. https://doi.org/10.1097/00006534-198508000-00028
MLA
Towpik E, et al.. "The potential use of cyclosporine in reconstructive surgery.." Plastic and reconstructive surgery, vol. 76, no. 2, 1985, pp. 312-22.
PMID
3895263
Abstract
Cyclosporine, the first of a new generation of selective immunosuppressive agents, has already proved to be of exceptional value in human organ transplantation; however, its role in human reconstructive surgery remains to be established. The possibility that short-term treatment could be sufficient for indefinite survival of bone, muscle, nerve, and vein allografts is attractive and might provoke changes in prevailing attitudes regarding the use of allogenous tissues in reconstructive procedures. Cyclosporine may start a new line of immunosuppressive agents with more potent therapeutic effect and less potential toxicity. This new generation of drugs, together with the experience in tissue transfer amassed by plastic surgeons during the last decade, may eventually result in unprecedented possibilities in surgical reconstruction.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 해부 | bone
|
scispacy | 1 | ||
| 해부 | muscle
|
scispacy | 1 | ||
| 해부 | nerve
|
scispacy | 1 | ||
| 해부 | vein allografts
|
scispacy | 1 | ||
| 해부 | tissues
|
scispacy | 1 | ||
| 해부 | line
|
scispacy | 1 | ||
| 해부 | tissue
|
scispacy | 1 | ||
| 약물 | cyclosporine
|
C0010592
cyclosporine
|
scispacy | 1 | |
| 질환 | toxicity
|
C0040539
Toxicity aspects
|
scispacy | 1 | |
| 기타 | human organ
|
scispacy | 1 | ||
| 기타 | human
|
scispacy | 1 |
MeSH Terms
Animals; Bone Transplantation; Cyclosporins; Dogs; Extremities; Graft Rejection; Graft Survival; Humans; Muscles; Nerve Regeneration; Peripheral Nerves; Rats; Skin Transplantation; Surgery, Plastic; Transplantation, Homologous; Veins; Wound Healing
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