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Deciphering the role of HMGA2 and let-7 microRNAs in myelodysplastic neoplasms with bone marrow fibrosis.

2/5 보강

Leukemia & lymphoma 📖 저널 OA 8.7% 2022~2026 2026 Vol.67(5) p. 1109-1115 MicroRNA in disease regulation

TL;DR It is suggested that let-7 miRNAs may serve as prognostic biomarkers and therapeutic targets in fibrotic MDS, whereas HMGA2 appears less predictive.

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

환자: MDS, while four members of the let-7 family (let-7a, let-7b, let-7c, let-7d) were specifically assessed in those with bone marrow fibrosis

I · Intervention 중재 / 시술

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C · Comparison 대조 / 비교

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O · Outcome 결과 / 결론

A novel positive correlation between HMGA2 and let-7d was also identified. These findings suggest that let-7 miRNAs may serve as prognostic biomarkers and therapeutic targets in fibrotic MDS, whereas HMGA2 appears less predictive.

OpenAlex 토픽 · MicroRNA in disease regulation Chromatin Remodeling and Cancer Acute Myeloid Leukemia Research

Vlachopoulou D, Kontandreopoulou CN, Diamantopoulos PT, Syriopoulou S, Stafylidis C, Katsiampoura P

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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