Duodenal leiomyoma: a case report of upper gastrointestinal hemorrhage from a giant duodenal tumor.
증례보고
2/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
추출되지 않음
I · Intervention 중재 / 시술
a successful resection of the tumor with no postoperative complications
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSION] Reported is the largest case of an 11.9 cm giant duodenal leiomyoma with life-threatening gastrointestinal hemorrhage, providing the first comprehensive radiological-histopathological correlation for a giant duodenal leiomyoma. Surgical resection remains the primary treatment to confirm the pathological diagnosis of benign leiomyoma and manage symptoms.
OpenAlex 토픽 ·
Gastrointestinal Tumor Research and Treatment
Soft tissue tumors and treatment
Soft tissue tumor case studies
[INTRODUCTION] Duodenal leiomyoma is a rare tumor, originating in the intestinal wall smooth muscle, making up <0.1% of all gastrointestinal tumors.
APA
Morgan MacKenzie, Benjamin MacKenzie, et al. (2026). Duodenal leiomyoma: a case report of upper gastrointestinal hemorrhage from a giant duodenal tumor.. International journal of surgery case reports, 138(4), 1481-1486. https://doi.org/10.1097/RC9.0000000000000354
MLA
Morgan MacKenzie, et al.. "Duodenal leiomyoma: a case report of upper gastrointestinal hemorrhage from a giant duodenal tumor.." International journal of surgery case reports, vol. 138, no. 4, 2026, pp. 1481-1486.
PMID
41938421 ↗
Abstract 한글 요약
[INTRODUCTION] Duodenal leiomyoma is a rare tumor, originating in the intestinal wall smooth muscle, making up <0.1% of all gastrointestinal tumors. The majority are discovered incidentally on endoscopy due to the small size of tumors at presentation. Larger duodenal leiomyomas may present with anemia from gastrointestinal hemorrhage.
[CASE PRESENTATION] A 67-year-old male presented with life-threatening upper gastrointestinal hemorrhage. Magnetic resonance imaging identified an 11.9 × 8.7 cm submucosal mass in the second portion of the duodenum adjacent to the pancreatic head. An urgent upper endoscopy confirmed active hemorrhage, which was controlled with endoscopic clips. The patient underwent a successful resection of the tumor with no postoperative complications.
[DISCUSSION] The diagnosis of duodenal leiomyomas remains challenging due to the lack of symptom manifestations. The differential diagnosis for a duodenal soft tissue mass includes gastrointestinal stromal tumor, solitary fibrous tumors, schwannoma, lymphoma, duodenal adenocarcinoma, and leiomyosarcoma. Radiographically, leiomyomas have typical imaging characteristics similar to skeletal muscle with marked T2 hypointensity, gradual enhancement on post contrast images, and the absence of extensive lesional necrosis. Surgical resection allows pathological confirmation of tissue diagnosis. Histopathologically, leiomyoma exhibits bland smooth muscle cells, with a low Ki67 proliferative index and absence of mitotic figures. Leiomyoma immunohistochemistry profile is positive for smooth muscle antigen and desmin.
[CONCLUSION] Reported is the largest case of an 11.9 cm giant duodenal leiomyoma with life-threatening gastrointestinal hemorrhage, providing the first comprehensive radiological-histopathological correlation for a giant duodenal leiomyoma. Surgical resection remains the primary treatment to confirm the pathological diagnosis of benign leiomyoma and manage symptoms.
[CASE PRESENTATION] A 67-year-old male presented with life-threatening upper gastrointestinal hemorrhage. Magnetic resonance imaging identified an 11.9 × 8.7 cm submucosal mass in the second portion of the duodenum adjacent to the pancreatic head. An urgent upper endoscopy confirmed active hemorrhage, which was controlled with endoscopic clips. The patient underwent a successful resection of the tumor with no postoperative complications.
[DISCUSSION] The diagnosis of duodenal leiomyomas remains challenging due to the lack of symptom manifestations. The differential diagnosis for a duodenal soft tissue mass includes gastrointestinal stromal tumor, solitary fibrous tumors, schwannoma, lymphoma, duodenal adenocarcinoma, and leiomyosarcoma. Radiographically, leiomyomas have typical imaging characteristics similar to skeletal muscle with marked T2 hypointensity, gradual enhancement on post contrast images, and the absence of extensive lesional necrosis. Surgical resection allows pathological confirmation of tissue diagnosis. Histopathologically, leiomyoma exhibits bland smooth muscle cells, with a low Ki67 proliferative index and absence of mitotic figures. Leiomyoma immunohistochemistry profile is positive for smooth muscle antigen and desmin.
[CONCLUSION] Reported is the largest case of an 11.9 cm giant duodenal leiomyoma with life-threatening gastrointestinal hemorrhage, providing the first comprehensive radiological-histopathological correlation for a giant duodenal leiomyoma. Surgical resection remains the primary treatment to confirm the pathological diagnosis of benign leiomyoma and manage symptoms.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- Acquired L858R mutation following -TKI resistance in lung adenocarcinoma: a case report.
- Case Report: Secondary neurolymphomatosis successfully treated with sequential Bruton's tyrosine kinase inhibitor and bispecific antibody therapy.
- Primary mediastinal mucormycosis presenting with hoarseness: a case report.
- Apocrine Ductal Carcinoma Ex Pleomorphic Adenoma of the Breast: A Rare Case Report.
- Diagnostic Challenge of a Vascular Liver Tumor With Pulmonary Hemorrhagic Metastases: A Case Report.
- Pathological Study of Rare Malignant Cardiac Tumors: A Case Series of Five Patients.