Primary Cardiac Diffuse Large B-Cell Lymphoma: A Diagnostic Pitfall With Overlapping Imaging Features.
2/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
추출되지 않음
I · Intervention 중재 / 시술
dose-adjusted R-EPOCH chemotherapy, achieving complete metabolic response after 3 cycles
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
In selected cases, radiotherapy can provide temporary stabilization until tissue diagnosis is established. [TAKE-HOME MESSAGE] PCL requires individualized management in the absence of established guidelines.
OpenAlex 토픽 ·
Cardiac tumors and thrombi
Lymphoma Diagnosis and Treatment
CNS Lymphoma Diagnosis and Treatment
[BACKGROUND] Primary cardiac lymphoma (PCL) is an exceptionally rare cardiac malignancy with heterogeneous presentations and variable multimodality imaging features.
- 연구 설계 cross-sectional
APA
Hazal Ünlügenç, Bekir Serhat Yıldız, et al. (2026). Primary Cardiac Diffuse Large B-Cell Lymphoma: A Diagnostic Pitfall With Overlapping Imaging Features.. JACC. Case reports, 108015. https://doi.org/10.1016/j.jaccas.2026.108015
MLA
Hazal Ünlügenç, et al.. "Primary Cardiac Diffuse Large B-Cell Lymphoma: A Diagnostic Pitfall With Overlapping Imaging Features.." JACC. Case reports, 2026, pp. 108015.
PMID
42017852
Abstract
[BACKGROUND] Primary cardiac lymphoma (PCL) is an exceptionally rare cardiac malignancy with heterogeneous presentations and variable multimodality imaging features.
[CASE SUMMARY] A 60-year-old man presented with heart failure and complete atrioventricular block. Echocardiography revealed a massive infiltrative right atrial mass with pericardial effusion. The mass demonstrated malignant features on cross-sectional imaging. As biopsy was considered high risk and a definitive pathologic diagnosis was lacking, radiotherapy was initiated in the setting of a structural oncologic emergency to maintain clinical stability, and extracardiac biopsy ultimately established primary cardiac diffuse large B-cell lymphoma. The patient received dose-adjusted R-EPOCH chemotherapy, achieving complete metabolic response after 3 cycles.
[DISCUSSION] PCL and cardiac angiosarcoma can share overlapping imaging features that may delay diagnosis; early histopathological confirmation is pivotal to guide therapy. In selected cases, radiotherapy can provide temporary stabilization until tissue diagnosis is established.
[TAKE-HOME MESSAGE] PCL requires individualized management in the absence of established guidelines.
[CASE SUMMARY] A 60-year-old man presented with heart failure and complete atrioventricular block. Echocardiography revealed a massive infiltrative right atrial mass with pericardial effusion. The mass demonstrated malignant features on cross-sectional imaging. As biopsy was considered high risk and a definitive pathologic diagnosis was lacking, radiotherapy was initiated in the setting of a structural oncologic emergency to maintain clinical stability, and extracardiac biopsy ultimately established primary cardiac diffuse large B-cell lymphoma. The patient received dose-adjusted R-EPOCH chemotherapy, achieving complete metabolic response after 3 cycles.
[DISCUSSION] PCL and cardiac angiosarcoma can share overlapping imaging features that may delay diagnosis; early histopathological confirmation is pivotal to guide therapy. In selected cases, radiotherapy can provide temporary stabilization until tissue diagnosis is established.
[TAKE-HOME MESSAGE] PCL requires individualized management in the absence of established guidelines.