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Blinatumomab nonresponse correlates with poor survival after brexucabtagene autoleucel in B-cell ALL.

Blood 2026 Vol.147(17) p. 2011-2017 🌐 cited 2 CAR-T cell therapy research
OpenAlex 토픽 · CAR-T cell therapy research Acute Lymphoblastic Leukemia research Chronic Myeloid Leukemia Treatments

Srinagesh HK, Gupta V, Zhang A, Grunwald M, Connor M, Kota VK, Boccucci J, Ulrickson M, Pradeep R, Hill L, Tsai SB, O'Connor T, Sandhu K, Advani AS, Reshef R, Gordillo CA, Luskin MR, Chen EC, Lin C, Cassaday RD, Kopmar NE, Majhail NS, Battiwalla M, Strickland SA, Lee CJ, Bobillo SO, Hilal T, Park JH, Valtis YK, Faramand R, Solh MM, Guzowski C, Vasu S, Leonard JT, Tan V, Wang ES, McCauley R, Sasine J, Tang K, Miller K, Sutherland KC, Daunov M, Mohty R, Jamy O, Kumaran MV, Hoeg RT, Dykes KC, Logan AC, Othman T, Stock W, Schwartz M, Byrd K, Yalniz F, Bachanova V, Tracy S, Yaghmour G, Irizarry Gatell VM, Jackson CW, Oluwole OO, Dholaria B, O'Dwyer KM, Moore J, Roloff GW, Frey NV, Aldoss I, Shah BD, Oliai CH, Muffly LS

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In a real-world analysis of brexucabtagene autoleucel recipients with relapsed/refractory B-cell acute lymphoblastic leukemia (N = 278), lack of response to prior blinatumomab correlates with signific

🔬 핵심 임상 통계 (초록에서 자동 추출 — 원문 검증 권장)
  • 표본수 (n) 278

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BibTeX ↓ RIS ↓
APA Hrishikesh K. Srinagesh, Vishal Gupta, et al. (2026). Blinatumomab nonresponse correlates with poor survival after brexucabtagene autoleucel in B-cell ALL.. Blood, 147(17), 2011-2017. https://doi.org/10.1182/blood.2025031734
MLA Hrishikesh K. Srinagesh, et al.. "Blinatumomab nonresponse correlates with poor survival after brexucabtagene autoleucel in B-cell ALL.." Blood, vol. 147, no. 17, 2026, pp. 2011-2017.
PMID 41643192

Abstract

In a real-world analysis of brexucabtagene autoleucel recipients with relapsed/refractory B-cell acute lymphoblastic leukemia (N = 278), lack of response to prior blinatumomab correlates with significantly worse following chimeric antigen receptor T-cell therapy outcomes.

MeSH Terms

Humans; Antibodies, Bispecific; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Immunotherapy, Adoptive; Male; Female; Adult; Middle Aged; Adolescent; Young Adult; Antineoplastic Agents, Immunological

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