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Use of Oral Metformin Therapy for Therapy-Induced Hyperglycemia in Pediatric Patients With Acute Lymphoblastic Leukemia.

2/5 보강

Pediatric blood & cancer 📖 저널 OA 40.7% 2022~2026 2026 Vol.73(5) p. e70185 Childhood Cancer Survivors' Quality

TL;DR Although insulin remains the standard therapy, oral metformin presents a promising alternative due to its ease of use, lower risk of hypoglycemia, and noninvasive route of administration—factors that can significantly enhance patient comfort and quality of life.

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

49 patients), with 17 experiencing recurrence during re-induction.

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

[CONCLUSION] Oral metformin proved to be a safe and effective first-line option for managing TIH in pediatric ALL. Insulin therapy could be avoided in majority of the patients (73.4% in induction, 68.1% in re-induction), making this drug an attractive first-line option for children with treatment-induced non-severe hyperglycemia.

OpenAlex 토픽 · Childhood Cancer Survivors' Quality of Life Acute Lymphoblastic Leukemia research Chronic Lymphocytic Leukemia Research

Chakraborty A, Kalra M, Arya AD, Sachdeva A

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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