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Detective flow imaging contrast-enhanced EUS in solid pancreatic lesions.

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Endoscopic ultrasound 2024 Vol.13(4) p. 248-252
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유사 논문
P · Population 대상 환자/모집단
107 patients included in this retrospective single-center study, the histological diagnosis revealed 69 cases (64.
I · Intervention 중재 / 시술
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C · Comparison 대조 / 비교
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O · Outcome 결과 / 결론
[CONCLUSIONS] The novel technique DFI-EUS demonstrates a remarkable correlation with CE-EUS, exhibiting high sensitivity and specificity for the assessment of microvascularization in solid pancreatic lesions. This method eliminates the need for a contrast agent, thus carrying no risk of adverse effects.

Mulqui MV, Caillol F, Ratone JP, Hoibian S, Dahel Y, Meunier É, Archimbaud C, Giovannini M

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[BACKGROUND AND OBJECTIVES] Detective flow imaging EUS (DFI-EUS) is a new technology that detects fine vessels and low-flow velocity without contrast agents, used in real time during EUS, with a bette

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APA Mulqui MV, Caillol F, et al. (2024). Detective flow imaging contrast-enhanced EUS in solid pancreatic lesions.. Endoscopic ultrasound, 13(4), 248-252. https://doi.org/10.1097/eus.0000000000000076
MLA Mulqui MV, et al.. "Detective flow imaging contrast-enhanced EUS in solid pancreatic lesions.." Endoscopic ultrasound, vol. 13, no. 4, 2024, pp. 248-252.
PMID 39318752 ↗

Abstract

[BACKGROUND AND OBJECTIVES] Detective flow imaging EUS (DFI-EUS) is a new technology that detects fine vessels and low-flow velocity without contrast agents, used in real time during EUS, with a better resolution compared to usual technologies such as color Doppler and eFLOW. The aim of this study was to compare DFI-EUS with contrast-enhanced EUS (CE-EUS) for the evaluation of vascularization in solid pancreatic lesions.

[METHODS] We included patients who had a pancreatic mass visualized by EUS, with recorded images of their assessment in DFI-EUS and CE-EUS techniques and a histological diagnosis confirmed malignant tumors or a minimum of 1-year follow-up for benign lesions.

[RESULTS] Of the 107 patients included in this retrospective single-center study, the histological diagnosis revealed 69 cases (64.5%) of pancreatic adenocarcinoma, 18 cases (16.8%) of neuroendocrine tumors (NETs), and 10 cases (9.3%) of metastases from nonpancreatic cancers. A smaller proportion (9.4%) exhibited other lesions. As a result, the incidence of intralesional microvascularization was 43.9% with DFI-EUS and 48.6% with CE-EUS, indicating a positive correlation between the 2 techniques ( = 0.0001). Compared to CE-EUS, DFI-EUS exhibited sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 88.5%, 98.2%, 97.9%, and 90%, respectively, for the detection of intralesional vessels.

[CONCLUSIONS] The novel technique DFI-EUS demonstrates a remarkable correlation with CE-EUS, exhibiting high sensitivity and specificity for the assessment of microvascularization in solid pancreatic lesions. This method eliminates the need for a contrast agent, thus carrying no risk of adverse effects.

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