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The efficacy and safety profile of third-line treatment in patients with metastatic pancreatic adenocarcinoma.

1/5 보강
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 📖 저널 OA 8.1% 2024: 5/43 OA 2025: 3/71 OA 2026: 4/34 OA 2024~2026 2025 Vol.25(2) p. 266-274
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
257 patients with mPDAC and progressive disease after first-line treatment with gemcitabine-based regimens and second-line treatment with liposomal irinotecan plus 5-fluorouracil and leucovorin at five Taiwanese medical centers from 2018 to 2022.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
43 of 77 patients (56 %) experienced at least one grade 3 or 4 toxicity. [CONCLUSION] In real-world settings, patients with mPDAC receiving third-line chemotherapy may have a moderate survival advantage, although clinicians should carefully select patients owing to high incidence of grade 3/4 toxicities.

Lan CC, Chiu TJ, Hung CY, Yeh KY, Lu CH, Chen YY


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