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Future of Pancreatic Cancer Therapy: Getting Better, But not Good Enough Ye.

Archives of medical research 2025 Vol.56(8) p. 103336

Klose J, Doebereiner J, Sunami Y, Rebelo A, Ronellenfitsch U, Kleeff J

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Diagnosis of pancreatic cancer is generally regarded as dismal with poor prognosis due to advanced stage at presentation and limited treatment options.

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APA Klose J, Doebereiner J, et al. (2025). Future of Pancreatic Cancer Therapy: Getting Better, But not Good Enough Ye.. Archives of medical research, 56(8), 103336. https://doi.org/10.1016/j.arcmed.2025.103336
MLA Klose J, et al.. "Future of Pancreatic Cancer Therapy: Getting Better, But not Good Enough Ye.." Archives of medical research, vol. 56, no. 8, 2025, pp. 103336.
PMID 41172872

Abstract

Diagnosis of pancreatic cancer is generally regarded as dismal with poor prognosis due to advanced stage at presentation and limited treatment options. In the last years, treatment options for patients with pancreatic cancer, even in advanced stages of disease, improved. Beside tailored-approaches including chemotherapies in neo or adjuvant intention, new targets as well as vaccination has been implemented into therapeutic strategies. Additionally, embedded into individual treatment strategies, surgical approached were refined providing the potential chance for cure even in metastatic disease. The aim of this review article is to describe current and further treatment options for patients with pancreatic cancer showing promising results. However, more efforts are needed to further improve patients' prognosis.

MeSH Terms

Humans; Pancreatic Neoplasms; Prognosis; Immunotherapy