[Successful Transfusion-Free Surgery Based on Patient-Blood-Management Program for Four Jehovah's Witness Patients with Resectable Borderline or Unresectable Pancreatic Duct Adenocarcinoma].

In the case of borderline resectable or unresectable locally advanced pancreatic cancer, the indication for surgical resection is considered after preoperative chemotherapy(radiation)and reevaluation of the patient's condition. During neoadjuvant chemotherapy, many patients show progressive hematocytopenia due to bone marrow suppression;hence, careful perioperative blood management has a significant impact on surgical resection procedures and outcomes regarding short-term or long-term prognoses. In this study, we report successful cases of transfusion-free surgery for initially borderline resectable and unresectable pancreatic cancer in 4 patients for whom transfusion was not an option, using the PBM treatment program.