Adipose whispers to mast cells for accelerating immune evasion in pancreatic cancer.
1/5 보강
The mechanisms connecting obesity to pancreatic cancer progression remain poorly defined.
APA
Rousseau L, Ho PC (2025). Adipose whispers to mast cells for accelerating immune evasion in pancreatic cancer.. Cell metabolism, 37(12), 2296-2297. https://doi.org/10.1016/j.cmet.2025.10.018
MLA
Rousseau L, et al.. "Adipose whispers to mast cells for accelerating immune evasion in pancreatic cancer.." Cell metabolism, vol. 37, no. 12, 2025, pp. 2296-2297.
PMID
41338175 ↗
Abstract 한글 요약
The mechanisms connecting obesity to pancreatic cancer progression remain poorly defined. A new study reveals that extracellular vesicles from visceral adipose tissue reprogram immune cells through a cathepsin A-pseudouridine-mast cell axis, uncovering how obesity drives immune evasion and resistance to checkpoint blockade therapy in pancreatic cancer.
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