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Tumor-associated Pancreatitis Mimicking Autoimmune Pancreatitis in a Young Male: A Case of Main Duct IPMC.

Internal medicine (Tokyo, Japan) 2025

Kawanishi M, Douhara A, Ishida K, Nakatsuji M, Hamato N, Nakagawa K, Tsutsumi M, Nakatani T

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We report a rare case of intraductal papillary mucinous carcinoma (IPMC) in a young male who initially presented with imaging findings suggestive of autoimmune pancreatitis (AIP) and was later diagnos

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APA Kawanishi M, Douhara A, et al. (2025). Tumor-associated Pancreatitis Mimicking Autoimmune Pancreatitis in a Young Male: A Case of Main Duct IPMC.. Internal medicine (Tokyo, Japan). https://doi.org/10.2169/internalmedicine.6037-25
MLA Kawanishi M, et al.. "Tumor-associated Pancreatitis Mimicking Autoimmune Pancreatitis in a Young Male: A Case of Main Duct IPMC.." Internal medicine (Tokyo, Japan), 2025.
PMID 41443858

Abstract

We report a rare case of intraductal papillary mucinous carcinoma (IPMC) in a young male who initially presented with imaging findings suggestive of autoimmune pancreatitis (AIP) and was later diagnosed with tumor-associated pancreatitis. Despite symptom resolution with conservative treatment, follow-up imaging revealed a pancreatic tumor. Surgical resection confirmed the presence of IPMC with adenocarcinoma components. This case highlights the importance of excluding malignancy even in young patients with AIP-like features. Given the limited sensitivity of FDG-PET for early stage tumors, adjunctive modalities such as endoscopic ultrasound (EUS) and serial pancreatic juice aspiration cytological examination (SPACE) should be actively considered.

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