← 뒤로

Changing treatment outcomes in metastatic and recurrent pancreatic cancer: a real-world comparison before and after the availability of nanoliposomal irinotecan.

1/5 보강

Japanese journal of clinical oncology 📖 저널 OA 17.2% 2022~2026 2026 Vol.56(3) p. 299-308

PICO 자동 추출 (휴리스틱, conf 3/4)

P · Population 대상 환자/모집단

426 patients (Group A/B: 230/196) were included.

I · Intervention 중재 / 시술

second-line chemotherapy after gemcitabine with nab-paclitaxel (GnP) between April 2015 and September 2024 at our hospital

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

Multivariate analysis revealed that treatment after the introduction of nal-IRI plus 5-FU/LV was an independent prognostic factor for OS-2 (hazard ratio, 0.75; P < .01). [CONCLUSION] The introduction of nal-IRI plus 5-FU/LV was associated with improved second-line treatment outcomes, providing a new combination regimen with acceptable toxicity in metastatic or recurrent pancreatic cancer.

Mie T, Ozaka M, Okamoto T, Suzuki K, Sato Y, Hirai T

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

Fatal error: Uncaught PDOException: SQLSTATE[42000]: Syntax error or access violation: 1064 You have an error in your SQL syntax; check the manual that corresponds to your MariaDB server version for the right syntax to use near 'JSON)) ORDER BY n_sources DESC LIMIT 6' at line 3 in /home/prsinsight/public_html/app/core/Database.php:33 Stack trace: #0 /home/prsinsight/public_html/app/core/Database.php(33): PDOStatement->execute() #1 /home/prsinsight/public_html/app/models/WikiPage.php(190): App\Core\Database::fetchAll() #2 /home/prsinsight/public_html/app/views/paper/show.php(671): App\Models\WikiPage::backlinksForPaper() #3 /home/prsinsight/public_html/app/core/View.php(32): include('...') #4 /home/prsinsight/public_html/app/core/View.php(15): App\Core\View->capture() #5 /home/prsinsight/public_html/app/core/Controller.php(21): App\Core\View->render() #6 /home/prsinsight/public_html/app/controllers/PaperController.php(372): App\Core\Controller->render() #7 [internal function]: App\Controllers\PaperController->show() #8 /home/prsinsight/public_html/app/core/Router.php(48): call_user_func_array() #9 /home/prsinsight/public_html/app/core/Router.php(34): App\Core\Router->call() #10 /home/prsinsight/public_html/index.php(286): App\Core\Router->dispatch() #11 {main} thrown in /home/prsinsight/public_html/app/core/Database.php on line 33