Comment on: Pasco ST Et Al. "Challenge-Specific Modulation of Responses to Adjuvant-Induced Innate Immune Memory".
2/5 보강
TL;DR
The diagram highlights the therapeutic potential of PERK-targeting strategies in disrupting cancer cell growth and promoting programmed cell death in modulating pancreatic cancer cell fate.
OpenAlex 토픽 ·
Endoplasmic Reticulum Stress and Disease
interferon and immune responses
Phagocytosis and Immune Regulation
The diagram highlights the therapeutic potential of PERK-targeting strategies in disrupting cancer cell growth and promoting programmed cell death in modulating pancreatic cancer cell fate.
APA
M Vijayasimha, M. Srikanth (2026). Comment on: Pasco ST Et Al. "Challenge-Specific Modulation of Responses to Adjuvant-Induced Innate Immune Memory".. Immunology, 177(4), 641-642. https://doi.org/10.1111/imm.70118
MLA
M Vijayasimha, et al.. "Comment on: Pasco ST Et Al. "Challenge-Specific Modulation of Responses to Adjuvant-Induced Innate Immune Memory".." Immunology, vol. 177, no. 4, 2026, pp. 641-642.
PMID
41630565 ↗
Abstract 한글 요약
This schematic illustrates the role of endoplasmic reticulum (ER) stress and PERK inhibition in modulating pancreatic cancer cell fate. ER stress activates the PERK pathway, which contributes to tumor cell survival. Pharmacologic inhibition of PERK, as depicted, leads to two downstream effects: decreased cellular proliferation and increased apoptosis. The diagram highlights the therapeutic potential of PERK-targeting strategies in disrupting cancer cell growth and promoting programmed cell death.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
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