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TET3 Mediates 5hmC Level and Promotes Tumorigenesis by Activating AMPK Pathway in Papillary Thyroid Cancer.

1/5 보강
International journal of endocrinology 2022 Vol.2022() p. 2658727
Retraction 확인
출처
PubMed DOI PMC

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
환자: thyroid cancer, which can reduce the tumor recurrence rate, morbidity, and mortality effectively
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
TET3-mediated 5hmC can regulate the transcription of AMPK pathway-related genes to activate the AMPK pathway and autophagy and therefore promote PTC proliferation. These findings provide a preclinical rationale for the design of novel therapeutic strategies for this target to improve the clinical outcome of patients with PTC.

Chi J, Zhang W, Li Y, Zhao J, Zheng X, Gao M

📖 무료 전문 🟢 PMC 전문 PMC9217609
PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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