The relationship between papillary thyroid cancer and triglyceride/glucose index, which is an indicator of insulin resistance.
1/5 보강
[OBJECTIVE] The incidence of thyroid cancer and metabolic syndrome has been increasing at the same rate over the past few decades.
- Specificity 49.2%
APA
Alkurt EG, Şahin F, et al. (2022). The relationship between papillary thyroid cancer and triglyceride/glucose index, which is an indicator of insulin resistance.. European review for medical and pharmacological sciences, 26(17), 6114-6120. https://doi.org/10.26355/eurrev_202209_29629
MLA
Alkurt EG, et al.. "The relationship between papillary thyroid cancer and triglyceride/glucose index, which is an indicator of insulin resistance.." European review for medical and pharmacological sciences, vol. 26, no. 17, 2022, pp. 6114-6120.
PMID
36111913 ↗
Abstract 한글 요약
[OBJECTIVE] The incidence of thyroid cancer and metabolic syndrome has been increasing at the same rate over the past few decades. We hypothesized that there would be a direct relationship between thyroid papillary cancer and triglyceride/glucose index (TyG).
[PATIENTS AND METHODS] A total of 382 operated patients were divided into two groups: patients operated on for papillary thyroid cancer and for non-malignant reasons. Each patient's age, gender, operation times, presence of neck dissection, serum thyroid-stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroxine (FT4), fasting blood glucose and triglyceride levels were scanned retrospectively from the archive system.
[RESULTS] TyG index was statistically higher in the malignant group. Receiver operating characteristic (ROC) curves obtained for TyG levels at the time of diagnosis of thyroid papillary cancer were AUC: 0.608. The threshold value for TyG was 6,252. The sensitivity of this value was 62.8% and the specificity was 49.2%.
[CONCLUSIONS] In this study, we investigated the predictive effect of the TyG index in differentiating thyroid papillary carcinoma from non-malignant thyroid lesions. We concluded that the TgY index can be used to identify people at high risk of thyroid papillary cancer and to plan treatment.
[PATIENTS AND METHODS] A total of 382 operated patients were divided into two groups: patients operated on for papillary thyroid cancer and for non-malignant reasons. Each patient's age, gender, operation times, presence of neck dissection, serum thyroid-stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroxine (FT4), fasting blood glucose and triglyceride levels were scanned retrospectively from the archive system.
[RESULTS] TyG index was statistically higher in the malignant group. Receiver operating characteristic (ROC) curves obtained for TyG levels at the time of diagnosis of thyroid papillary cancer were AUC: 0.608. The threshold value for TyG was 6,252. The sensitivity of this value was 62.8% and the specificity was 49.2%.
[CONCLUSIONS] In this study, we investigated the predictive effect of the TyG index in differentiating thyroid papillary carcinoma from non-malignant thyroid lesions. We concluded that the TgY index can be used to identify people at high risk of thyroid papillary cancer and to plan treatment.
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