[Correlation between BRAF mutation and aggressive biological behavior of papillary thyroid carcinoma].
1/5 보강
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
160 patients with papillary thyroid carcinoma who underwent surgical treatment in the Affiliated Cancer Hospital of Zhengzhou University from October 2020 to November 2021 were retrospectively included.
I · Intervention 중재 / 시술
BRAF gene detection
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
There was no significant correlation between the mutation of BRAF and aggressive factors such as age (=0.917), single focal/multifocal tumor (=0.673), tumor size (=0.360), tumor invasion (=0.150) and regional lymph node metastasis (=0.406). Therefore, for papillary thyroid cancer, mutations in a single gene like BRAF fail to determine more active diagnosis and treatment.
The current study analyzed the mutation rate of BRAF in papillary thyroid carcinoma patients and the correlation between BRAF mutation and aggressive biological behavior of papillary thyroid carcinoma
APA
Zhou B, Hei H, et al. (2023). [Correlation between BRAF mutation and aggressive biological behavior of papillary thyroid carcinoma].. Zhonghua yi xue za zhi, 103(14), 1060-1063. https://doi.org/10.3760/cma.j.cn112137-20220729-01657
MLA
Zhou B, et al.. "[Correlation between BRAF mutation and aggressive biological behavior of papillary thyroid carcinoma].." Zhonghua yi xue za zhi, vol. 103, no. 14, 2023, pp. 1060-1063.
PMID
37032157 ↗
Abstract 한글 요약
The current study analyzed the mutation rate of BRAF in papillary thyroid carcinoma patients and the correlation between BRAF mutation and aggressive biological behavior of papillary thyroid carcinoma. A total of 160 patients with papillary thyroid carcinoma who underwent surgical treatment in the Affiliated Cancer Hospital of Zhengzhou University from October 2020 to November 2021 were retrospectively included. All patients underwent BRAF gene detection. There were 37 males and 123 females, with a mean age of (46.5±11.1) years. The mutation rate of BRAF was 86.3% (138/160). There was no significant correlation between the mutation of BRAF and aggressive factors such as age (=0.917), single focal/multifocal tumor (=0.673), tumor size (=0.360), tumor invasion (=0.150) and regional lymph node metastasis (=0.406). Therefore, for papillary thyroid cancer, mutations in a single gene like BRAF fail to determine more active diagnosis and treatment.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
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