Features of mixed medullary thyroid tumors: An NCDB analysis of clinicopathologic characteristics and survival.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
101 patients: 421 MMPTC (0.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
MMFTC had a worse OS compared to all groups (63.32%,p < 0.001). [CONCLUSION] Patients with MMFTC had significantly worse OS compared to DTC, portending a worse prognosis.
[BACKGROUND] Mixed medullary-papillary thyroid carcinoma (MMPTC) and mixed medullary-follicular thyroid carcinoma (MMFTC) are rare variants with little known regarding behavior and prognosis.
- p-value p < 0.001
APA
Sandilos G, Lou J, et al. (2023). Features of mixed medullary thyroid tumors: An NCDB analysis of clinicopathologic characteristics and survival.. American journal of surgery, 226(1), 53-58. https://doi.org/10.1016/j.amjsurg.2023.02.006
MLA
Sandilos G, et al.. "Features of mixed medullary thyroid tumors: An NCDB analysis of clinicopathologic characteristics and survival.." American journal of surgery, vol. 226, no. 1, 2023, pp. 53-58.
PMID
36775791 ↗
Abstract 한글 요약
[BACKGROUND] Mixed medullary-papillary thyroid carcinoma (MMPTC) and mixed medullary-follicular thyroid carcinoma (MMFTC) are rare variants with little known regarding behavior and prognosis.
[METHODS] Using the National Cancer Database (NCDB), demographics, clinicopathologic features, treatment, and overall survival (OS) from patients with MMPTC and MMFTC were compared to more prevalent subtypes.
[RESULTS] There were 296,101 patients: 421 MMPTC (0.14%), 133 MMFTC (0.04%), 263,140 PTC (88.87%), 24,208 FTC (8.18%) and 8,199 MTC (2.77%). Compared to PTC, MMPTC and MMFTC patients were older (p < 0.001) with a higher Charlson-Deyo comorbidity index (p < 0.001). Mixed tumors exhibited lower rates of nodal disease but more distant metastases compared to PTC (p < 0.001). MMPTC demonstrated lower estimated 10-year OS than PTC and FTC (76.04%vs 89.04% and 81.95%,p < 0.001), yet higher than MTC (70.29%,p < 0.001). MMFTC had a worse OS compared to all groups (63.32%,p < 0.001).
[CONCLUSION] Patients with MMFTC had significantly worse OS compared to DTC, portending a worse prognosis.
[METHODS] Using the National Cancer Database (NCDB), demographics, clinicopathologic features, treatment, and overall survival (OS) from patients with MMPTC and MMFTC were compared to more prevalent subtypes.
[RESULTS] There were 296,101 patients: 421 MMPTC (0.14%), 133 MMFTC (0.04%), 263,140 PTC (88.87%), 24,208 FTC (8.18%) and 8,199 MTC (2.77%). Compared to PTC, MMPTC and MMFTC patients were older (p < 0.001) with a higher Charlson-Deyo comorbidity index (p < 0.001). Mixed tumors exhibited lower rates of nodal disease but more distant metastases compared to PTC (p < 0.001). MMPTC demonstrated lower estimated 10-year OS than PTC and FTC (76.04%vs 89.04% and 81.95%,p < 0.001), yet higher than MTC (70.29%,p < 0.001). MMFTC had a worse OS compared to all groups (63.32%,p < 0.001).
[CONCLUSION] Patients with MMFTC had significantly worse OS compared to DTC, portending a worse prognosis.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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