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Effects of apitherapy against salivary gland disorder after radioactive iodine therapy for differentiated thyroid cancer.

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Annals of nuclear medicine 📖 저널 OA 17% 2022: 0/4 OA 2023: 0/3 OA 2024: 0/3 OA 2025: 5/16 OA 2026: 3/26 OA 2022~2026 2023 Vol.37(8) p. 462-469
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 3/4)

유사 논문
P · Population 대상 환자/모집단
120 patients with DTC who underwent total thyroidectomy were divided into the apitherapy group (group A, n = 60) and the control group (group B, n = 60).
I · Intervention 중재 / 시술
total thyroidectomy were divided into the apitherapy group (group A, n = 60) and the control group (group B, n = 60)
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Group A did not present significant differences in the maximum uptake ratio and washout ratio. [CONCLUSIONS] Apitherapy can have protective effects against salivary gland disorder associated with RAIT in patients with DTC.

Nomura K, Nakayama M, Okizaki A

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📝 환자 설명용 한 줄

[OBJECTIVE] Sialadenitis and salivary gland disorders are complications of radioactive iodine therapy (RAIT) that affect the quality of life of patients with differentiated thyroid cancer (DTC).

🔬 핵심 임상 통계 (초록에서 자동 추출 — 원문 검증 권장)
  • 표본수 (n) 60
  • p-value P < 0.01
  • p-value P < 0.05

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APA Nomura K, Nakayama M, Okizaki A (2023). Effects of apitherapy against salivary gland disorder after radioactive iodine therapy for differentiated thyroid cancer.. Annals of nuclear medicine, 37(8), 462-469. https://doi.org/10.1007/s12149-023-01845-w
MLA Nomura K, et al.. "Effects of apitherapy against salivary gland disorder after radioactive iodine therapy for differentiated thyroid cancer.." Annals of nuclear medicine, vol. 37, no. 8, 2023, pp. 462-469.
PMID 37149836 ↗

Abstract

[OBJECTIVE] Sialadenitis and salivary gland disorders are complications of radioactive iodine therapy (RAIT) that affect the quality of life of patients with differentiated thyroid cancer (DTC). The current study aimed to provide evidence on the protective effect of apitherapy on salivary gland function during RAIT in patients with DTC.

[METHODS] In total, 120 patients with DTC who underwent total thyroidectomy were divided into the apitherapy group (group A, n = 60) and the control group (group B, n = 60). Group A received 2.5 g of acacia honey three times daily after each meal during admission for RAIT. Statistical analyses were performed using the Saxon test (which is used to evaluate saliva volume) and salivary gland scintigraphy (which is applied to assess maximum uptake ratio and washout ratio).

[RESULTS] Compared with group B, group A presented with a more significantly positive change in the rate of amount of saliva before and after treatment (P < 0.01). Group B presented a significant decrease in the maximum uptake ratio of the bilateral parotid and submandibular glands on salivary gland scintigraphy (P < 0.05) and washout ratio of all salivary glands (P < 0.05). Group A did not present significant differences in the maximum uptake ratio and washout ratio.

[CONCLUSIONS] Apitherapy can have protective effects against salivary gland disorder associated with RAIT in patients with DTC.

🏷️ 키워드 / MeSH 📖 같은 키워드 OA만

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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반