The impact of lymph node ratio on disease recurrence in papillary thyroid microcarcinoma.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
50 patients (36 female [72%]; median age 47 years [range: 19-84]) who underwent LN clearance (28 central [56%] vs 22 central + lateral [44%]) were analysed.
I · Intervention 중재 / 시술
resection of their microPTC with concomitant LN clearance between 2005 and 2018 were identified
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
A higher LNR seems to be associated with recurrence. Additional studies are needed to further clarify these findings and to assess the possible role of LNR in treatment and surveillance.
[INTRODUCTION] Lymph node (LN) metastases in papillary thyroid microcarcinomas (microPTCs) are common.
- 추적기간 61 months
APA
de Jong MC, Mahipal M, et al. (2023). The impact of lymph node ratio on disease recurrence in papillary thyroid microcarcinoma.. Annals of the Royal College of Surgeons of England, 105(7), 632-638. https://doi.org/10.1308/rcsann.2022.0094
MLA
de Jong MC, et al.. "The impact of lymph node ratio on disease recurrence in papillary thyroid microcarcinoma.." Annals of the Royal College of Surgeons of England, vol. 105, no. 7, 2023, pp. 632-638.
PMID
37652084 ↗
Abstract 한글 요약
[INTRODUCTION] Lymph node (LN) metastases in papillary thyroid microcarcinomas (microPTCs) are common. The lymph node ratio (LNR) has been proposed as a risk factor for recurrence in papillary thyroid cancer. However, its relevance in microPTC is undetermined.
[METHODS] Patients who underwent resection of their microPTC with concomitant LN clearance between 2005 and 2018 were identified. The LNR was calculated as the ratio of positive LNs to the total number of LNs.
[RESULTS] Data on 50 patients (36 female [72%]; median age 47 years [range: 19-84]) who underwent LN clearance (28 central [56%] vs 22 central + lateral [44%]) were analysed. Positive LNs were found in over two-thirds of the patients ( = 34; 68%). After a median follow-up of 61 months, 14 patients (28%) had developed recurrence. Positive LNs were not found to impact recurrence-free survival; extranodal extension and an LNR ≥ 0.26 were found to significantly increase the risk of recurrence on unadjusted analyses ( < 0.05).
[CONCLUSIONS] LN metastases are frequent among patients with microPTC. A higher LNR seems to be associated with recurrence. Additional studies are needed to further clarify these findings and to assess the possible role of LNR in treatment and surveillance.
[METHODS] Patients who underwent resection of their microPTC with concomitant LN clearance between 2005 and 2018 were identified. The LNR was calculated as the ratio of positive LNs to the total number of LNs.
[RESULTS] Data on 50 patients (36 female [72%]; median age 47 years [range: 19-84]) who underwent LN clearance (28 central [56%] vs 22 central + lateral [44%]) were analysed. Positive LNs were found in over two-thirds of the patients ( = 34; 68%). After a median follow-up of 61 months, 14 patients (28%) had developed recurrence. Positive LNs were not found to impact recurrence-free survival; extranodal extension and an LNR ≥ 0.26 were found to significantly increase the risk of recurrence on unadjusted analyses ( < 0.05).
[CONCLUSIONS] LN metastases are frequent among patients with microPTC. A higher LNR seems to be associated with recurrence. Additional studies are needed to further clarify these findings and to assess the possible role of LNR in treatment and surveillance.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
같은 제1저자의 인용 많은 논문 (1)
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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