Papillary Thyroid Carcinoma in a Pediatric Patient With β-Thalassemia.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
환자: β-thalassemia have been reported in the adult literature, but there have been none in pediatrics
I · Intervention 중재 / 시술
total thyroidectomy and histological examination confirmed the diagnosis
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
This is the first reported case of PTC in a pediatric patient with β-thalassemia. The incidence of thyroid cancer in patients with β-thalassemia is currently unknown; however, there may be utility in routine surveillance of this patient population.
β-Thalassemia is characterized by the abnormal synthesis of β-hemoglobin chains resulting in hemolytic anemia.
APA
Choleva L, Wilkes M (2023). Papillary Thyroid Carcinoma in a Pediatric Patient With β-Thalassemia.. JCEM case reports, 1(6), luad131. https://doi.org/10.1210/jcemcr/luad131
MLA
Choleva L, et al.. "Papillary Thyroid Carcinoma in a Pediatric Patient With β-Thalassemia.." JCEM case reports, vol. 1, no. 6, 2023, pp. luad131.
PMID
37946725 ↗
Abstract 한글 요약
β-Thalassemia is characterized by the abnormal synthesis of β-hemoglobin chains resulting in hemolytic anemia. Treatment involves frequent blood transfusions, which leads to deposition of iron in many organs, including endocrine glands. To date, several cases of papillary thyroid cancer (PTC) in patients with β-thalassemia have been reported in the adult literature, but there have been none in pediatrics. Here we report on an female adolescent with β-thalassemia who initially presented for evaluation of secondary amenorrhea. On examination, her thyroid gland was asymmetric, firm in consistency, with palpable lymph nodes along the right anterior cervical chain. A thyroid ultrasound revealed an enlarged right lobe containing 3 focal hypoechoic masses with calcific foci. Biopsy was consistent with PTC. She underwent total thyroidectomy and histological examination confirmed the diagnosis. Her postoperative course was uncomplicated and she was started on replacement therapy with levothyroxine. This is the first reported case of PTC in a pediatric patient with β-thalassemia. The incidence of thyroid cancer in patients with β-thalassemia is currently unknown; however, there may be utility in routine surveillance of this patient population.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- Mechanism of cancer-associated fibroblast-driven thyroid cancer dedifferentiation via the ZFP57-PKM2 axis-mediated lactate secretion and therapeutic intervention with resveratrol.
- CHI3L1 Is Associated With TP53 Signaling and Promotes Papillary Thyroid Carcinoma Progression.
- Visualizing malignant progression: in situ CD109-based spatial immunofluorescence assay delineates papillary to anaplastic thyroid carcinoma transformation within the tumor microenvironment.
- The Role of Mean Platelet Volume (MPV) in Thyroid Cancers: A Scoping Review.
- Bilaterality in papillary thyroid carcinoma: long-term outcomes and predictive factors.
- IL-6 regulates the polarization of Dectin-1 macrophages to weaken immune escape in thyroid cancer.