Hysterectomy and thyroid cancer risk: A systematic review and meta-analysis.
메타분석
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
추출되지 않음
I · Intervention 중재 / 시술
a hysterectomy have an elevated relative risk of thyroid cancer
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Significant publication bias was not detected. [CONCLUSIONS] Our findings help with decision making around these surgeries.
[BACKGROUND] Incidence rates of thyroid cancer have increased.
- 95% CI 1.48-1.81
- 연구 설계 meta-analysis
APA
Fabiani R, Rosignoli P, et al. (2023). Hysterectomy and thyroid cancer risk: A systematic review and meta-analysis.. Global epidemiology, 6, 100122. https://doi.org/10.1016/j.gloepi.2023.100122
MLA
Fabiani R, et al.. "Hysterectomy and thyroid cancer risk: A systematic review and meta-analysis.." Global epidemiology, vol. 6, 2023, pp. 100122.
PMID
37860218 ↗
Abstract 한글 요약
[BACKGROUND] Incidence rates of thyroid cancer have increased. Recent studies findings suggest that women who underwent a hysterectomy have an elevated relative risk of thyroid cancer. The aim of our meta-analysis is to summarize the evidence about the association between hysterectomy and thyroid cancer risk.
[METHODS] PubMed, Web of Science, and Scopus database were searched for studies published up to 5 September 2023. The PRISMA statement was followed. Heterogeneity was explored with Q statistic and the I2 statistic. Publication bias was assessed with Begg's and Egger's tests.
[RESULTS] Sixteen studies met the criteria. The pooled analysis showed a significantly 64% increment of thyroid cancer risk in association with any hysterectomy (OR 1.64, 95% CI 1.48-1.81; I2 = 28.68%, = 0.156). Hysterectomy without oophorectomy was a stronger predictor of risk than hysterectomy with oophorectomy. The pooled analysis of data regarding hysterectomy without oophorectomy showed a statistically significant increment of thyroid cancer risk by 59%. Hysterectomy with oophorectomy was associated with an increase of thyroid cancer risk of 39% (OR 1.39, 95% CI 1.16-1.67; I2 = 42.10%, = 0.049). Significant publication bias was not detected.
[CONCLUSIONS] Our findings help with decision making around these surgeries.
[METHODS] PubMed, Web of Science, and Scopus database were searched for studies published up to 5 September 2023. The PRISMA statement was followed. Heterogeneity was explored with Q statistic and the I2 statistic. Publication bias was assessed with Begg's and Egger's tests.
[RESULTS] Sixteen studies met the criteria. The pooled analysis showed a significantly 64% increment of thyroid cancer risk in association with any hysterectomy (OR 1.64, 95% CI 1.48-1.81; I2 = 28.68%, = 0.156). Hysterectomy without oophorectomy was a stronger predictor of risk than hysterectomy with oophorectomy. The pooled analysis of data regarding hysterectomy without oophorectomy showed a statistically significant increment of thyroid cancer risk by 59%. Hysterectomy with oophorectomy was associated with an increase of thyroid cancer risk of 39% (OR 1.39, 95% CI 1.16-1.67; I2 = 42.10%, = 0.049). Significant publication bias was not detected.
[CONCLUSIONS] Our findings help with decision making around these surgeries.