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A study of variation in therapeutic approach to low-risk differentiated thyroid cancer in the UK.

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The Journal of laryngology and otology 📖 저널 OA 12.1% 2021: 1/2 OA 2022: 0/6 OA 2023: 1/8 OA 2024: 3/9 OA 2025: 5/12 OA 2026: 2/4 OA 2021~2026 2024 Vol.138(1) p. 83-88
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Maniam P, Ishii H, Stechman MJ, Watkinson J, Farnell K, Kim D, Nixon IJ

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[BACKGROUND] The British Thyroid Association and American Thyroid Association guideline definitions for low-risk differentiated thyroid cancers are susceptible to differing interpretations, resulting

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APA Maniam P, Ishii H, et al. (2024). A study of variation in therapeutic approach to low-risk differentiated thyroid cancer in the UK.. The Journal of laryngology and otology, 138(1), 83-88. https://doi.org/10.1017/S0022215123000841
MLA Maniam P, et al.. "A study of variation in therapeutic approach to low-risk differentiated thyroid cancer in the UK.." The Journal of laryngology and otology, vol. 138, no. 1, 2024, pp. 83-88.
PMID 37194495 ↗

Abstract

[BACKGROUND] The British Thyroid Association and American Thyroid Association guideline definitions for low-risk differentiated thyroid cancers are susceptible to differing interpretations, resulting in different clinical management in the UK.

[OBJECTIVE] To explore the national effect of these guidelines on the management of low-risk differentiated thyroid cancers.

[METHODS] Anonymised questionnaires were sent to multidisciplinary teams performing thyroidectomies in the UK. Risk factors that multidisciplinary teams considered important when managing low-risk differentiated thyroid cancers were established.

[RESULTS] Most surgeons (71 out of 75; 94.7 per cent) confirmed they were core multidisciplinary team members. More than 80 per cent of respondents performed at least 30 hemi- and/or total thyroidectomies per annum. A majority of multidisciplinary teams (50 out of 75; 66.7 per cent) followed British Thyroid Association guidelines. Risk factors considered important when managing low-risk differentiated thyroid cancers included: type of tumour histology findings (87.8 per cent), tumour size of greater than 4 cm (86.5 per cent), tumour stage T (85.1 per cent) and central neck node involvement (85.1 per cent). Extent of thyroid surgery (e.g. hemi- or total thyroidectomy) was highly variable for low-risk differentiated thyroid cancers.

[CONCLUSION] Management of low-risk differentiated thyroid cancers is highly variable, leading to a heterogeneous patient experience.

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