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Differentiated thyroid cancer: a focus on post-operative thyroid hormone replacement and thyrotropin suppression therapy.

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Endocrine 📖 저널 OA 26.4% 2022: 9/35 OA 2023: 14/49 OA 2024: 14/69 OA 2025: 18/63 OA 2026: 8/22 OA 2022~2026 2024 Vol.83(2) p. 251-258
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Gigliotti BJ, Jasim S

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[PURPOSE] This review focuses on post-operative thyroid hormone replacement and thyrotropin suppression therapy in patients with differentiated thyroid cancer.

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APA Gigliotti BJ, Jasim S (2024). Differentiated thyroid cancer: a focus on post-operative thyroid hormone replacement and thyrotropin suppression therapy.. Endocrine, 83(2), 251-258. https://doi.org/10.1007/s12020-023-03548-8
MLA Gigliotti BJ, et al.. "Differentiated thyroid cancer: a focus on post-operative thyroid hormone replacement and thyrotropin suppression therapy.." Endocrine, vol. 83, no. 2, 2024, pp. 251-258.
PMID 37824045 ↗

Abstract

[PURPOSE] This review focuses on post-operative thyroid hormone replacement and thyrotropin suppression therapy in patients with differentiated thyroid cancer.

[METHODS] A clinical review.

[RESULTS] Differentiated thyroid cancers (DTC), including papillary and follicular thyroid cancers, have an excellent prognosis and their management leverages a unique set of clinical tools arising from homology to the normal thyroid follicular cell. Surgery is the cornerstone of initial management, and post-operative care often requires thyroid hormone replacement therapy, which may be approached with the intent of physiologic normalization or used pharmacologically to suppress TSH as part of a DTC treatment.

[CONCLUSION] Management of DTC and approaches to TSH suppression are tailored to an individual's risk of DTC recurrence and are adjusted to a patient's clinical status and comorbidities over time with the goal of mitigating risk and maximizing benefit.

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