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A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer.

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Clinical cancer research : an official journal of the American Association for Cancer Research 📖 저널 OA 54.1% 2022: 3/4 OA 2023: 6/8 OA 2024: 8/14 OA 2025: 57/92 OA 2026: 81/165 OA 2022~2026 2024 Vol.30(7) p. 1220-1222
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Lechner MG, Brent GA

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Advanced differentiated thyroid cancer that is resistant to radioactive iodine therapy may become responsive with a unique treatment combination of chloroquine and vorinostat.

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APA Lechner MG, Brent GA (2024). A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research, 30(7), 1220-1222. https://doi.org/10.1158/1078-0432.CCR-23-3503
MLA Lechner MG, et al.. "A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer.." Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 30, no. 7, 2024, pp. 1220-1222.
PMID 38197869 ↗

Abstract

Advanced differentiated thyroid cancer that is resistant to radioactive iodine therapy may become responsive with a unique treatment combination of chloroquine and vorinostat. This treatment was demonstrated in cellular and animal models of thyroid cancer to inhibit endocytosis of the plasma membrane-bound iodine transporter, NIS, and restore iodine uptake. See related article by Read et al., p. 1352.

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