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Pulmonary Metastatic Follicular Thyroid Carcinoma Without Intrathyroidal Primary Thyroid Cancer.

증례보고 1/5 보강
AACE clinical case reports 2024 Vol.10(4) p. 123-126
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 3/4)

유사 논문
P · Population 대상 환자/모집단
2 cases of multifocal pulmonary follicular thyroid cancer without a primary source and no other site of metastasis have been reported.
I · Intervention 중재 / 시술
261 mCi of radioactive iodine
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[DISCUSSION] Approximately 2 cases of multifocal pulmonary follicular thyroid cancer without a primary source and no other site of metastasis have been reported. [CONCLUSION] Pulmonary follicular thyroid cancer without a primary source and no other site of metastasis is extremely rare.

Saberi S, Burris N, Wong KK, Brown NA, Giordano T, Esfandiari NH

📝 환자 설명용 한 줄

[BACKGROUND/OBJECTIVE] Follicular thyroid cancer without an intrathyroidal primary cancer is rare.

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↓ .bib ↓ .ris
APA Saberi S, Burris N, et al. (2024). Pulmonary Metastatic Follicular Thyroid Carcinoma Without Intrathyroidal Primary Thyroid Cancer.. AACE clinical case reports, 10(4), 123-126. https://doi.org/10.1016/j.aace.2024.03.006
MLA Saberi S, et al.. "Pulmonary Metastatic Follicular Thyroid Carcinoma Without Intrathyroidal Primary Thyroid Cancer.." AACE clinical case reports, vol. 10, no. 4, 2024, pp. 123-126.
PMID 39100638 ↗

Abstract

[BACKGROUND/OBJECTIVE] Follicular thyroid cancer without an intrathyroidal primary cancer is rare. We present a patient with multifocal pulmonary metastatic follicular thyroid cancer without apparent cancer within her thyroid.

[CASE REPORT] A 44-year-old woman was referred to the thyroid cancer clinic via telemedicine for evaluation of intrapulmonary thyroid tissue. Her past medical history included Roux-en-Y gastric bypass and hysterectomy with bilateral oophorectomy. Six months prior, abdominal computed tomography (CT) showed incidental bilateral lung nodules. Chest CT demonstrated 4 solid left and 1 solid right lung nodules. Lung nodule core biopsy revealed benign thyroid tissue. Thyroid ultrasound showed bilateral subcentimeter anechoic nodules. Chest CT 6 months after initial CT demonstrated stable lung nodules. The levels of thyroid-stimulating hormone, serum thyroglobulin, and thyroglobulin antibody were 1.63 mIU/L (reference range, 0.3-5.5 mIU/L), 40.9 ng/mL (reference range, 0-35 ng/mL), and <1 IU/mL (reference range, <4), respectively. Positron emission tomography/CT showed fluorodeoxyglucose-avid lung lesions measuring 1.5, 1.1, and 2.2 cm and other subcentimeter pulmonary nodules. Repeat lung core biopsy showed thyroid tissue with microfollicular architecture, favoring metastatic follicular carcinoma with neuroblastoma-RAS gene () mutation. Total thyroidectomy performed showed multinodular hyperplasia without thyroid cancer. Her postoperative radioiodine scan demonstrated bilateral iodine-avid pulmonary nodules, a serum thyroglobulin level of 179.8 ng/mL, a thyroid-stimulating hormone level of 151.3 mIU/L, and undetectable serum thyroglobulin antibody. She received 261 mCi of radioactive iodine. Fourteen months later, chest CT revealed decreased lung nodules and a serum thyroglobulin level of 0.7 ng/mL.

[DISCUSSION] Approximately 2 cases of multifocal pulmonary follicular thyroid cancer without a primary source and no other site of metastasis have been reported.

[CONCLUSION] Pulmonary follicular thyroid cancer without a primary source and no other site of metastasis is extremely rare.

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