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Clinical, Pathological, and Immunohistochemical Predictors of Cause-Specific Mortality in Papillary Thyroid Cancer: Multivariate Analysis.

환자-대조 1/5 보강
Bulletin of experimental biology and medicine 2024 Vol.177(3) p. 353-358
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Bakarev MA, Ivanov AA, Lushnikova EL

📝 환자 설명용 한 줄

The association of clinical, pathological, and immunohistochemical characteristics of papillary thyroid cancer with cause-specific mortality was analyzed in a case-control study within a cohort of pat

🔬 핵심 임상 통계 (초록에서 자동 추출 — 원문 검증 권장)
  • p-value p<0.001
  • 연구 설계 case-control

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↓ .bib ↓ .ris
APA Bakarev MA, Ivanov AA, Lushnikova EL (2024). Clinical, Pathological, and Immunohistochemical Predictors of Cause-Specific Mortality in Papillary Thyroid Cancer: Multivariate Analysis.. Bulletin of experimental biology and medicine, 177(3), 353-358. https://doi.org/10.1007/s10517-024-06188-8
MLA Bakarev MA, et al.. "Clinical, Pathological, and Immunohistochemical Predictors of Cause-Specific Mortality in Papillary Thyroid Cancer: Multivariate Analysis.." Bulletin of experimental biology and medicine, vol. 177, no. 3, 2024, pp. 353-358.
PMID 39134811 ↗

Abstract

The association of clinical, pathological, and immunohistochemical characteristics of papillary thyroid cancer with cause-specific mortality was analyzed in a case-control study within a cohort of patients from the Altai Regional Oncology Center. According to multivariate analysis, the independent predictors of fatal outcome within 10 years after surgery in patients living in Altai region are nuclear pattern of Hsp70 expression, thyroid capsular invasion, Ki-67 expression index >7%, and patient's age >45 years for men and >50 years for women. The prognostic model based on these features contributes to a significant improvement in the individual prognostic performance for papillary thyroid cancer in the modeling sample. The model has high statistical significance (χ=64.73; p<0.001) and discriminative power (AUC=0.950, prediction accuracy 88.5%).

🏷️ 키워드 / MeSH 📖 같은 키워드 OA만

… 외 1개

🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반