Sex differences and racial/ethnic disparities in the presentation and treatment of medullary thyroid cancer.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
6154 patients, 68.
I · Intervention 중재 / 시술
guideline-concordant surgery
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Black patients were less likely to undergo guideline-concordant surgery (OR 0.70, p = 0.022). [CONCLUSIONS] Male and non-White patients with MTC more frequently present with advanced disease, and Black patients are less likely to undergo guideline-concordant surgery.
[BACKGROUND] This study assessed for disparities in the presentation and management of medullary thyroid cancer (MTC).
APA
Kalva S, Ginzberg SP, et al. (2024). Sex differences and racial/ethnic disparities in the presentation and treatment of medullary thyroid cancer.. American journal of surgery, 234, 19-25. https://doi.org/10.1016/j.amjsurg.2024.02.009
MLA
Kalva S, et al.. "Sex differences and racial/ethnic disparities in the presentation and treatment of medullary thyroid cancer.." American journal of surgery, vol. 234, 2024, pp. 19-25.
PMID
38365554
Abstract
[BACKGROUND] This study assessed for disparities in the presentation and management of medullary thyroid cancer (MTC).
[METHODS] Patients with MTC (2010-2020) were identified from the National Cancer Database. Differences in disease presentation and likelihood of guideline-concordant surgical management (total thyroidectomy and resection of ≥1 lymph node) were assessed by sex and race/ethnicity.
[RESULTS] Of 6154 patients, 68.2% underwent guideline-concordant surgery. Tumors >4 cm were more likely in men (vs. women: OR 2.47, p < 0.001) and Hispanic patients (vs. White patients: OR 1.52, p = 0.001). Non-White patients were more likely to have distant metastases (Black: OR 1.63, p = 0.002; Hispanic: OR 1.44, p = 0.038) and experienced longer time to surgery (Black: HR 0.66, p < 0.001; Hispanic: HR 0.71, p < 0.001). Black patients were less likely to undergo guideline-concordant surgery (OR 0.70, p = 0.022).
[CONCLUSIONS] Male and non-White patients with MTC more frequently present with advanced disease, and Black patients are less likely to undergo guideline-concordant surgery.
[METHODS] Patients with MTC (2010-2020) were identified from the National Cancer Database. Differences in disease presentation and likelihood of guideline-concordant surgical management (total thyroidectomy and resection of ≥1 lymph node) were assessed by sex and race/ethnicity.
[RESULTS] Of 6154 patients, 68.2% underwent guideline-concordant surgery. Tumors >4 cm were more likely in men (vs. women: OR 2.47, p < 0.001) and Hispanic patients (vs. White patients: OR 1.52, p = 0.001). Non-White patients were more likely to have distant metastases (Black: OR 1.63, p = 0.002; Hispanic: OR 1.44, p = 0.038) and experienced longer time to surgery (Black: HR 0.66, p < 0.001; Hispanic: HR 0.71, p < 0.001). Black patients were less likely to undergo guideline-concordant surgery (OR 0.70, p = 0.022).
[CONCLUSIONS] Male and non-White patients with MTC more frequently present with advanced disease, and Black patients are less likely to undergo guideline-concordant surgery.
MeSH Terms
Adult; Aged; Female; Humans; Male; Middle Aged; Carcinoma, Neuroendocrine; Ethnicity; Healthcare Disparities; Hispanic or Latino; Retrospective Studies; Sex Factors; Thyroid Neoplasms; Thyroidectomy; United States; Racial Groups