Oncocytic carcinoma of the thyroid: Conclusions from a 20-year patient cohort.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: OCA at a single tertiary care hospital from 2000 to 2021
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Radioactive iodine was used as adjunct therapy in 77%. [CONCLUSION] OCA has distinct features that distinguish it from other DTCs, and additional focused studies will help clarify the aggressive nature, treatment options, and prognosis of the disease.
[BACKGROUND] Oncocytic carcinoma (OCA) was recently reclassified as a distinct differentiated thyroid carcinoma (DTC).
- 표본수 (n) 14
APA
Gruszczynski NR, Hasan SS, et al. (2024). Oncocytic carcinoma of the thyroid: Conclusions from a 20-year patient cohort.. Head & neck, 46(8), 2042-2047. https://doi.org/10.1002/hed.27700
MLA
Gruszczynski NR, et al.. "Oncocytic carcinoma of the thyroid: Conclusions from a 20-year patient cohort.." Head & neck, vol. 46, no. 8, 2024, pp. 2042-2047.
PMID
38390640
Abstract
[BACKGROUND] Oncocytic carcinoma (OCA) was recently reclassified as a distinct differentiated thyroid carcinoma (DTC). Given its rarity, OCA studies are limited. This study describes the characteristics of OCA in a 20-year cohort.
[METHODS] Retrospective analysis of patients with OCA at a single tertiary care hospital from 2000 to 2021.
[RESULTS] Fifty-one OCA patients (22M:29F) were identified. The mean age at diagnosis was 60.3 years; 90% presented as palpable mass; 24% had a family history of thyroid cancer. None had vocal fold paresis. On ultrasound, most tumors were solid and hypoechoic. FNA (n = 14) showed Bethesda-4 lesions in 93%. All were treated surgically. Histologically, 63% demonstrated angioinvasion, 35% had lymphovascular invasion, and 15% had extrathyroidal extension. Radioactive iodine was used as adjunct therapy in 77%.
[CONCLUSION] OCA has distinct features that distinguish it from other DTCs, and additional focused studies will help clarify the aggressive nature, treatment options, and prognosis of the disease.
[METHODS] Retrospective analysis of patients with OCA at a single tertiary care hospital from 2000 to 2021.
[RESULTS] Fifty-one OCA patients (22M:29F) were identified. The mean age at diagnosis was 60.3 years; 90% presented as palpable mass; 24% had a family history of thyroid cancer. None had vocal fold paresis. On ultrasound, most tumors were solid and hypoechoic. FNA (n = 14) showed Bethesda-4 lesions in 93%. All were treated surgically. Histologically, 63% demonstrated angioinvasion, 35% had lymphovascular invasion, and 15% had extrathyroidal extension. Radioactive iodine was used as adjunct therapy in 77%.
[CONCLUSION] OCA has distinct features that distinguish it from other DTCs, and additional focused studies will help clarify the aggressive nature, treatment options, and prognosis of the disease.