Characterization of microRNA-223-3p as a novel promoter of cell proliferation and invasion in papillary thyroid carcinoma.
1/5 보강
Papillary thyroid carcinoma (PTC), the most common thyroid cancer, has been linked to various molecular alterations.
APA
Pan X, Liu J, et al. (2025). Characterization of microRNA-223-3p as a novel promoter of cell proliferation and invasion in papillary thyroid carcinoma.. Journal of cell communication and signaling, 19(1), e12057. https://doi.org/10.1002/ccs3.12057
MLA
Pan X, et al.. "Characterization of microRNA-223-3p as a novel promoter of cell proliferation and invasion in papillary thyroid carcinoma.." Journal of cell communication and signaling, vol. 19, no. 1, 2025, pp. e12057.
PMID
39712860 ↗
Abstract 한글 요약
Papillary thyroid carcinoma (PTC), the most common thyroid cancer, has been linked to various molecular alterations. This study focuses on microRNA-223-3p, whose upregulated expression in PTC tissues appears to enhance tumor growth and cellular dysfunctions. Our findings demonstrate that microRNA-223-3p significantly promotes cell proliferation, invasion, and migration and induces epithelial-mesenchymal transition (EMT). Additionally, neurofibromatosis type 2 (NF2) is identified as a direct target, suggesting that microRNA-223-3p could be crucial in PTC pathogenesis and may offer a target for therapeutic intervention.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
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