Reprogramming of Thyroid Cancer Metabolism: from Mechanism to Therapeutic Strategy.
Thyroid cancer as one of the most prevalent malignancies of endocrine system, has raised public concern and more research on its mechanism and treatment.
APA
Wan Y, Li G, et al. (2025). Reprogramming of Thyroid Cancer Metabolism: from Mechanism to Therapeutic Strategy.. Molecular cancer, 24(1), 74. https://doi.org/10.1186/s12943-025-02263-4
MLA
Wan Y, et al.. "Reprogramming of Thyroid Cancer Metabolism: from Mechanism to Therapeutic Strategy.." Molecular cancer, vol. 24, no. 1, 2025, pp. 74.
PMID
40069775
Abstract
Thyroid cancer as one of the most prevalent malignancies of endocrine system, has raised public concern and more research on its mechanism and treatment. And metabolism-based therapies have advanced rapidly, for the exclusive metabolic profiling of thyroid cancer. In thyroid cancer cells, plenty of metabolic pathways are reprogrammed to accommodate tumor microenvironment. In this review, we initiatively summarize recent progress in the full-scale thyroid cancer metabolic rewiring and the interconnection of various metabolites. We also discuss the efficacy and prospect of metabolic targeted detection as well as therapy. Comprehending metabolic mechanism and characteristics of thyroid cancer roundly will be highly beneficial to managing individual patients.
MeSH Terms
Humans; Thyroid Neoplasms; Tumor Microenvironment; Metabolic Networks and Pathways; Animals; Cellular Reprogramming; Metabolomics
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