Exploring the Rare Hobnail Variant of Papillary Thyroid Carcinoma: A Case Report.
증례보고
1/5 보강
The hobnail variant of papillary thyroid carcinoma (HPTC) is a rare but highly aggressive form of thyroid cancer, associated with a more severe clinical course and significantly poorer prognosis compa
APA
Bouayed FZ, Berhili S, et al. (2025). Exploring the Rare Hobnail Variant of Papillary Thyroid Carcinoma: A Case Report.. Cureus, 17(6), e86323. https://doi.org/10.7759/cureus.86323
MLA
Bouayed FZ, et al.. "Exploring the Rare Hobnail Variant of Papillary Thyroid Carcinoma: A Case Report.." Cureus, vol. 17, no. 6, 2025, pp. e86323.
PMID
40688912 ↗
Abstract 한글 요약
The hobnail variant of papillary thyroid carcinoma (HPTC) is a rare but highly aggressive form of thyroid cancer, associated with a more severe clinical course and significantly poorer prognosis compared to conventional PTC. To be classified as HPTC, a tumor must contain at least 30% of cells exhibiting hobnail-micropapillary features. These cells are characterized by distinctive papillary cytomorphology, including a hobnail-like appearance, the presence of papillae and micropapillae, high nuclear-to-cytoplasmic ratios, apically located nuclei, and prominent nucleoli. Additionally, some studies have reported associations between HPTC and specific genetic mutations, such as BRAFV600E, TP53, and TERT. In this article, we present the case of a 58-year-old male diagnosed with HPTC, managed with radiotherapy.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- Ketamine as a Novel Solution for Opioid-Refractory Pain in Radiation Necrosis.
- A Case of Warthin-Like Variant of Papillary Thyroid Cancer.
- A Challenging Diagnosis of Papillary Thyroid Carcinoma Arising From Malignant Struma Ovarii.
- Comparative Prognostic Analysis of the Tall Cell Subtype of Papillary Thyroid Carcinoma With the Conventional Subtype Following the WHO 2022 Revision: An Indian Cohort Study.
- The Long Journey towards Personalized Targeted Therapy in Poorly Differentiated Thyroid Carcinoma (PDTC): A Case Report and Systematic Review.
- Case Report: Primary Squamous Cell Carcinoma of the Orbit in a Patient With Carney's Syndrome Treated With Multidisciplinary Approaches.